Evaluation of Different Diagnostic Techniques for Malaria in a Tertiary Health Care Centre, Karnataka
Journal Title: Indian Journal of Pathology: Research and Practice - Year 2017, Vol 6, Issue 1
Abstract
Context: Malaria is endemic in tropics and subtropics with India contributing to 75% of the cases in South East Region. The early diagnosis of malaria is essential to treat patients and to prevent complications especially in cerebral malaria. Aims: To evaluate the diagnostic accuracy of different techniques available like Peripheral smear, Quantitative Buffy coat (QBC), and Rapid Diagnostic tests (RDT) in the diagnosis of malaria. Settings and Design: Prospective study for duration of one year. Methods and Material: Blood samples from all clinically suspected cases of malaria were routinely subjected to peripheral smear examination, QBC & RDT for the presence of malaria parasite. Statistical analysis used: Sensitivity, Specificity, Positive predictive value and Negative predictive value were analyzed using standard formulae. Results: Sensitivity, specificity, Positive Predictive value and Negative predictive values were 100%, 99.6%, 97% and 100% for QBC and 100%, 99.2%, 95% and 100% for RDT respectively. Conclusions: RDTs are equally or more sensitive and specific than peripheral smear and QBC. Newer Pf /Pv specific antigen card can distinguish mixed and PF infections unlike old Pf/ Pan RDTs. However further studies are required to assess cost effectiveness and efficiency of different RDTs.
Authors and Affiliations
Padmaja Kulkarni
Keywords
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- EP ID EP462266
- DOI 10.21088/ijprp.2278.148X.6117.22
- Views 82
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