Granulomatous Mastitis: A Masquerading Entity
Journal Title: Indian Journal of Pathology: Research and Practice - Year 2017, Vol 6, Issue 2
Abstract
Introduction: Granulomatous mastitis (GM) is a rare chronic inflammatory lesion of breast of unknown etiology. This entity clinically and radiologically may simulate carcinoma and presents as palpable breast lump with history of associated pregnancy, lactation or history of oral contraceptive intake. Cytological diagnosis is difficult as microscopic features are non specific and overlaps with other etiologies. Aims/Objectives:To study clinical presentation and cytological features of granulomatous mastitis with histopathological correlation. Methods: Prospective study of 24 cases was done over a period of three years and diagnosed as granulomatous mastitis on FNAC. Clinical data were collected and histopathological correlation was done among 18 cases. Results: Study comprised of 24 cases of granulomatous mastitis with age group ranging from 18 to 48 years (mean age - 33 years). Out of 24 cases, 16 cases had history of taking oral contraceptive pills and 14 were lactating. All the patients presented with breast lump, with abscess in four cases and axillary lymphadenopathy in three cases. Diagnosis of granulomatous mastitis was done on cytology based on the presence of epithelioid cells either in granulomas or scattered along with multinucleated giant cells against background comprising predominantly of neutrophils. Histopathological correlation was done among 18 cases with 100% correlation. Conclusion: Granulomatous mastitis is essentially a diagnosis of exclusion, which can be established by fine needle cytology in majority of cases thereby preventing unnecessary surgeries. matous mastitis diagnosed on cytology with 100% histopathological correlation.
Authors and Affiliations
Punyashetty Kajal B.
Keywords
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- EP ID EP464198
- DOI 10.21088/ijprp.2278.148X.62(pt-II)17.10
- Views 108
- Downloads 0
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