Study on Acute Leukemia and their Karyotypic Abnormalities in Children
Journal Title: Indian Journal of Pathology: Research and Practice - Year 2018, Vol 7, Issue 9
Abstract
Malignant proliferative diseases affecting the white cell population results in acute or chronic leukemias and lymphomas. There are several categories of acute leukemias based on the cell of origin and are broadly divided into lymphoid leukemias and myeloid leukemias. Acute lymphoid leukemias are very common in children while Acute Myeloid leukemias are more often seen in older children and young adults. To analyse the morphologic subtypes of Acute leukemias in children using cytochemistry. To determine the type of acute leukemia and associated chromosomal abnormality, to assess the chemotherapeutic response of acute leukemias occurring in paediatric age group, to assess the prognostic significance of age, sex and leucocyte count in acute leukemias in children. Out of 45 cases of acute leukemias there were 33 cases of ALL and 12 cases of AML. Acute myeloid leukemias showed a wide range of chromosomal abnormality, interestingly the Acute myeloid leukemias was found to be on rise in the present study.
Authors and Affiliations
Mohd Irshad Ahmed
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