Study on Acute Leukemia and their Karyotypic Abnormalities in Children
Journal Title: Indian Journal of Pathology: Research and Practice - Year 2018, Vol 7, Issue 9
Abstract
Malignant proliferative diseases affecting the white cell population results in acute or chronic leukemias and lymphomas. There are several categories of acute leukemias based on the cell of origin and are broadly divided into lymphoid leukemias and myeloid leukemias. Acute lymphoid leukemias are very common in children while Acute Myeloid leukemias are more often seen in older children and young adults. To analyse the morphologic subtypes of Acute leukemias in children using cytochemistry. To determine the type of acute leukemia and associated chromosomal abnormality, to assess the chemotherapeutic response of acute leukemias occurring in paediatric age group, to assess the prognostic significance of age, sex and leucocyte count in acute leukemias in children. Out of 45 cases of acute leukemias there were 33 cases of ALL and 12 cases of AML. Acute myeloid leukemias showed a wide range of chromosomal abnormality, interestingly the Acute myeloid leukemias was found to be on rise in the present study.
Authors and Affiliations
Mohd Irshad Ahmed
Keywords
Related Articles
- EP ID EP529400
- DOI 10.21088/ijprp.2278.148X.7918.9
- Views 82
- Downloads 0
Objective Structured Practical Examination (OSPE) Verses Conventional Practical Examination (CPE): A Study in Pathology Subject among 2ndYear MBBS Students
Background: Conventional Practical Examination (CPE) or Viva only tests the overall performance of the students (cognitive domain) but other domains like psychomotor skills, comprehension and interpretation ability etc....
Accuracy of Triple Assessment in Diagnosing Breast Cancer with Histopathological Correlation
Introduction: Breast cancer is the leading cause of death in females, whose meticulous evaluation is required for an early diagnosis. Aims and objectives: In our study we evaluated the role of triple assessment in diagno...
Clinicopathological Study of Benign Skin Tumors
Background: Benign skin tumors constitute a small part of the surgical specimens. However, histopathologically, there is a wide variety of benign skin tumors. Aim and Objectives: To study the histopathology of benign sk...
Evaluation of Neonatal Thrombocytopenia: Incidence and Causes
Background: Thrombocytopenia is one of the commonly encountered haematological abnormalities in neonates admitted in NICU. Various factors such as ARDS, neonatal sepsis, meconium aspiration syndrome, neonatal hyperbiliru...
Evaluation of Prognostic Factors in 198Buccal Mucosa Cancer Patients: Univariate and Multivariate Analysis
Background: Buccal mucosa cancer is the most common oral subsitewhichis aggressive in nature, had high rate of locoregional recurrence and mortality in India. Objective: The aim of study was to evaluate prognostic factor...