Study on Acute Leukemia and their Karyotypic Abnormalities in Children
Journal Title: Indian Journal of Pathology: Research and Practice - Year 2018, Vol 7, Issue 9
Abstract
Malignant proliferative diseases affecting the white cell population results in acute or chronic leukemias and lymphomas. There are several categories of acute leukemias based on the cell of origin and are broadly divided into lymphoid leukemias and myeloid leukemias. Acute lymphoid leukemias are very common in children while Acute Myeloid leukemias are more often seen in older children and young adults. To analyse the morphologic subtypes of Acute leukemias in children using cytochemistry. To determine the type of acute leukemia and associated chromosomal abnormality, to assess the chemotherapeutic response of acute leukemias occurring in paediatric age group, to assess the prognostic significance of age, sex and leucocyte count in acute leukemias in children. Out of 45 cases of acute leukemias there were 33 cases of ALL and 12 cases of AML. Acute myeloid leukemias showed a wide range of chromosomal abnormality, interestingly the Acute myeloid leukemias was found to be on rise in the present study.
Authors and Affiliations
Mohd Irshad Ahmed
Keywords
Related Articles
- EP ID EP529400
- DOI 10.21088/ijprp.2278.148X.7918.9
- Views 63
- Downloads 0
Evaluation of Computed Tomography Guided Percutaneous Fine Needle Aspiration Cytology in the Diagnosis of Lung Lesions
Introduction: Computed Tomography (CT) guided percutaneous fine-needle aspiration cytology (FNAC) of suspicious lung lesions is a widely accepted diagnostic method with relatively low cost, negligible mortality and limit...
Detection of Seroprevalence and Baseline Titre of Brucella Agglutinins in Blood Donors of Dhule District
Introduction: Brucellosis is a major zoonosis in the developing countries including India. The reported incidence of human brucellosis in endemic areas varies widely, from <0.01 to >200 per lakh population. Despite being...
Study of Platelet Parameters in Women with Iron Deficiency Anaemia
Background: Several changes in platelet parameters have been reported in Iron deficiency anemia. But underlying mechanism between iron metabolism and megakaryopoiesis is not yet clear. Hence the aim of the study is to ev...
Expression of p63 in Benign, In-Situ and Invasive Ductal Carcinoma of Breast
Background: p63 is a member of p53 family of transcription factors which have important function in tumorogenesis and oncogenesis. It is involved in cellular differentiation and exposed in nuclei of myoepithelial cells o...
Soft Tissue Tumors: Incidence and Distribution in a Tertiary Care Centre
Background: Soft tissue tumors are mesenchymal proliferation, that occur in extraskeletal, non-epithelial tissue of the body, excluding the viscera, covering of brain and lymphoreticular system. Benign tumors are more co...