Evaluation of Fluorescein Diacetate Vital Staining Performance in Bacteriogical Follow-Up of Tuberculosis Patients in Kinshasa
Journal Title: International Journal of Medical Research Professionals - Year 2017, Vol 3, Issue 1
Abstract
Background: Resistants alcalo acido bacilli met during the follow-up of patients are declared as fail in the second or third month of treatment. However, the Ziehl used doesn’t distinguish the dead bacilli from those which are alive. Objective: To show the FDA pertinence in the patients monitoring under antituberculosis sufferer treatment. Methods: Study of prospective troop, comparing the sensitivity and specificity, as so the negatives and positives predictive values of three usual analyzes technical (Ziehl, Auramine, FDA) to the tuberculosis suffer subjects. The samples tested positives by the Ziehl, in the screening (testing) center and the tuberculosis Elonga treatment, have in addition been confronted for confirmation to the cultured of the Löwenstein-Jensens medium considered as reference test, to the Kinshasa Clinics University. Results: Sensitivity for the Ziehl was 83.3 % (IC95%:63.8-94.5) at the 2nd month, 90.5 % (IC95%: 68.2-98.3) at 3rd month and 100 % (IC95%: 80-100) at the 5th month of treatment. It’s was 100 % (IC95%: 80.8-100) at the 2nd,3rd, 5th, 6th and 8th month for the Auramine. For FDA, it’s was 100 % (IC95%: 82.8-100) for the 2nd month, and 100 % (IC95%: 80.8-100) at the 3th month. The results of the 3th month were identical at the 5th and 6th month of treatment. Sensitivity for the Ziehl was 83.3 % (IC95%:63.8-94.5) at the 2nd month, 90.5% (IC95%: 68.2-98.3) at 3rd month and 100% (IC95%: 80-100) at the 5th month of treatment. It’s was 100 % (IC95%: 80.8-100) at the 2nd, 3rd, 5th, 6th and 8th month for the Auramine. For FDA, it’s was 100 % (IC95%: 82.8-100) for the 2nd month, and 100 % (IC95%: 80.8-100) at the 3th month. The results of 3th month were identical at 5th and in the 6th month of treatment. Conclusion: Even though almost similar for the 3 technical after the 5th month, the indicators suggest a superiority of the FDA and the culture used as reference to the precocious steps of the follow-up.
Authors and Affiliations
Kabedi Bajani MJ, Kayembe Kalambay P, Kayembe Ntumba JM, Kashongwe Munongolo Z, Taba Kalulu M, Bisuta Fueza S, Mujangi Kadima B, Mbaya Kalumbu P, Muyembe tamfum JJ
Keywords
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- EP ID EP541602
- DOI 10.21276/ijmrp.2017.3.1.013
- Views 91
- Downloads 0
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