Evaluation of Histological Pattern in Patients Suffering From Tuberculosis with Enlarged Lymph Node: A Hospital Based Study
Journal Title: International Journal of Medical Research Professionals - Year 2018, Vol 4, Issue 1
Abstract
Background: Tuberculosis is a major public health problem worldwide. Mycobacterium tuberculosis is the culprit responsible for tuberculosis. Ziehl-Neelsen and fluorescent methods are generally used in identification of Mycobacterium tuberculosis. It is transmitted through air and person to person thus knowledge regarding transmission, diagnosis and cure holds an important role in prevention of disease. Aim: The aim of this study is to evaluate public awareness and attitude towards pulmonary tuberculosis. Materials and Methods: Fifty lymph nodes tissue biopsies which were diagnosed by conventional histopathology as having tuberculous lymphadenitis were reinvestigated. Sections were obtained from formalin-fixed paraffin wax processed tissues. Haematoxylin and eosin, ZN, and fluorescent methods were used for staining. Result: All specimens showed Histological pattern of tuberculosis lymphadenitis. All of the 100 specimens were proved as having histopathological pattern of tuberculosis lymphadenitis. The most major histological features were giant cell 85%, caseation 81%, epithelioid cells 80%. Only 5% cases showed positive for ZN and 11% showed positive result for fluorescent methods. Conclusion: ZN and fluorescent methods are not very useful. Physician should not completely rely on single diagnostic aids. Histopathology remains the best method for diagnosis.
Authors and Affiliations
Shailendra Singh Solanki
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- EP ID EP531278
- DOI 10.21276/ijmrp.2018.4.1.127
- Views 75
- Downloads 0
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