Evaluation of hypo lipidemic and antioxident properties of methanolic extract of leaves of Tectona grandis linn on Mithionine induced model in Wister albino rats
Journal Title: Indian Journal of Research in Pharmacy and Biotechnology - Year 2017, Vol 5, Issue 2
Abstract
The Methanolic extract of Tectona grandis leaves was subjected to phytochemical screening to find the chemical constituents present. The extract revealed the presence of carbohydrates, alkaloids, phytosterols, proteins & aminoacids, tannin, saponins and flavonoids. The extract was studied for anti-hyperlipidemic (hypolipidemic) activity with Methionine induced hyperlipidimic model which mimics hyperlipidemia in experimental animals. The extract was studied for anti-oxidant activity also. The effect of the Methanolic extract of the Tectona grandis on total cholesterol, triglycerides, LDL, HDL and VLDL levels were studied.
Authors and Affiliations
Sk Mallika, Sk Eesuf Pasha, Sk Khaleel, Prasanth Kumar
Developmental Genotoxicology and genotoxicity testing guidelines: an overview on erythromycin genotoxicity
Despite the growing knowledge of genome and its integrity, it is hard to know which pharmaceuticals can harm its structure and functioning. Before a drug reach to the phase IV clinical trial it have to pass the genotox...
Analytical method development for the simultaneous estimation of Hydrochlorothiazide and Atenolol in combined tablet formulation by RP-HPLC
A Simple, accurate, rapid, sensitive and precise Rp-Hplc method has been developed for estimation of Hydrochlorothiazide and Atenolol in tablet dosage form using PDA detector. A Reverse phase Thermo Hypersil ODS c18 co...
Study on dried fruits properties using osmotic method and response surface methodology
Dehydration or osmotic drying is a process in which partial or all food water removes through putting it in a hypertonic solution of sugar or salt. In this study, in order to determine optimized condition of apple slice...
BIOAVAILABILITY: CRITERIA FOR APPROVING A DRUG PRODUCT FOR MARKETING
FDA ensure that the drug product for marketing should be safe, effective and meet all applicable standards, for this FDA requires bioavailability/pharmacokinetic studies and, where necessary, bioequivalence studies for...
EVALUATION OF THE ASSOCIATION OF rs8052394 OF METALOTHIONEIN-1A GENE WITH TYPE 2 DIABETES MELLITUS IN NEPALESE POPULATION
Polymorphisms in metallothionein-1A gene associated with the risk of type 2 diabetes mellitus and its complications. Metallothioneine (MT) as a potent antioxidant can affect energy metabolism. The present study was und...