Evaluation of Hypoalbuminemia as a Predictor of Clinical Outcome in Critically Ill Children in Alexandria University Children's Hospital
Journal Title: Journal of Medical Science And clinical Research - Year 2018, Vol 6, Issue 1
Abstract
Outcome prediction is an important target in intensive care unit for providing information on patient outcomes for clinicians and family of critically ill patients. Hypoalbuminemia on admission is common in critical illness in all populations and proved to be a strong predictor of clinical outcome in adults. Because it is a simple, cheap and sensitive marker, it has been used for several purposes in adult Intensive Care Units (ICU) including outcome prediction. Although hypoalbuminemia is a common finding in critically ill children, there is a lack of data that evaluate its usefulness in predicting clinical outcome. In this retrospective study, we aimed to evaluate hypoalbuminemia as a predictor of clinical outcome in 487 critically ill children admitted to a tertiary hospital. Results showed that hypoalbuminemia was present at admission in 40.66% patients that increased to 53.8% during rest of the PICU stay. Hypoalbuminemia at admission was an independent predictor of mortality. Also, we found that patients with hypoalbuminemia at admission had a significantly higher Pediatric Logistic Organ Dysfunction score (PELOD), prolonged Pediatric Intensive Care Unit (PICU) stay and higher mortality. Patients with hypoalbuminemia during admission had significantly longer length of PICU stay, more need for mechanical ventilation, worse PELOD score, higher Pediatric Index of Mortality 2 (PIM2) score and higher mortality. Thus hypoalbuminemia at admission can be helpful for risk assessment and can be used as an outcome predictor in critically ill children.
Authors and Affiliations
Azza A. Moustafa
Keywords
Related Articles
- EP ID EP501956
- DOI -
- Views 83
- Downloads 0
Langer Giedion Syndrome with Absence of Bilateral Radial Arteries – A Rare Clinical Association
Langer Giedion syndrome, also known as Trichorhinophalangeal syndrome type 2 (OMIM 150230) is a rare multisystem disorder characterized by distinctive facial features and cartilaginous exostosis. It is a contiguous gene...
A Comparative Study of Variations in Estimated Age between maxillary and mandibular teeth of an individual using TCA Method
Human age estimation is of key importance in any forensic investigation. Assessment of age by counting the total cemental annulations is well documented as a reliable method for this purpose with variations of only 2-3 y...
Evaluation of Intrathecal Neostigmine in Different Doses Added to Xylocaine for Post Operative Analgesia
Intrathecal (IT) neostigmine has been used as an adjunct to spinal anaesthesia. The purpose of this study was to determine whether a combination of low-dose neostigmine IT would enhance analgesia of xylocaine IT, in pati...
Pseudo-Meigs Syndrome: A Case Report
Meigs syndrome is defined as the co-existence of hydrothorax and ascites with solid benign ovarian tumours, which resolve on removal of the tumour. Hydrothorax and ascites associated with pelvic tumours other than descri...
Breakbone Fever- Sonological Manifestations of Dengue
Dengue fever is a major cause of illness and death worldwide. The disease is caused by dengue virus which gets transmitted to humans by the bites of infected mosquitoes, Aedes (Ae.) aegypti and Ae. albopictus [1]. The di...