Evaluation of Lipid Peroxidation in Cases of Idiopathic Male Infertility
Journal Title: PARIPEX-Indian Journal of Research - Year 2016, Vol 5, Issue 11
Abstract
The lipid peroxides and their degradation products are highly toxic to spermatozoa and may play a major role in sperm dysfunction Oxidative stress (OS) is involved in low sperm quality and the etiology of male infertility. The measure of malondialdehyde MDA could be useful diagnostic tool for estimation of oxidative stress. One of the byproducts of lipid peroxidation is malondialdehyde, which has been used as an end product in biochemical assays to monitor the degree of peroxidative damage to spermatozoa. The aim of this study was to determine the level of malondialdehyde in seminal plasma of fertile and infertile men and investigate its relationship with sperm quality. Results showed that the MDA concentration in seminal plasma of unexplained infertile men was significantly higher than fertile men . These finding suggested that oxidative stress was involved in low sperm quality and the etiology of male infertility. The measure of MDA could be useful diagnostic tool for estimation of oxidative stress.
Authors and Affiliations
Dr. Alpana Tyagi, Dr. Hyacinth Highland, Dr. Rajula T
Keywords
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