Evaluation of oxidative stress in severe acute malnourished children at Malnutrition Treatment Centre.
Journal Title: International Journal of Medical Science and Innovative Research (IJMSIR) - Year 2018, Vol 3, Issue 7
Abstract
Malnutrition is one of the largest factors suppressing India's spectacular growth. This study was carried out to evaluate the effect of oxidative stress in severe acute malnourished children. Serum Malondialdehyde (MDA) level was determined in 50 severe acute malnourished (SAM) children (aged 6 months to 5 years) and 50 age and gender matched healthy controls. Mean serum MDA was found to be significantly raised in malnourished children as compared to healthy controls (p<0.001). From the present observations, it is evident that stress is created as a result of deficiency of nutrients in severe acute malnourished children. This stress leads to production of excess reactive oxygen species (ROS). These ROS leads to lipid peroxidation and consequent formation of MDA.
Authors and Affiliations
Amit Shandilya
Keywords
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