Evaluation of oxidative stress markers and antioxidant status in smokers
Journal Title: Medpulse International Journal of Biochemistry - Year 2019, Vol 9, Issue 2
Abstract
Aims and objective: Evaluation of oxidative stress markers and antioxidant status in Smokers. Material and methods: Study was conducted in Department of Biochemistry, LTMMC Sion Mumbai. 60 chronic smokers were tested for levels of MDA (Malondialdehyde), GSH (Glutathione) and SOD (Superoxide dismutase). Results were compared with 60 controls. Results and observations: Samples from patients showed increased MDA and decreased values of SOD and GSH when compared with controls and results were statistically significant. Discussion: Oxidative stress is harmful condition that occurs when there is excess of reactive oxygen species or decreased antioxidant level. It is evident from results that smoking increases the oxidative stress and decreases antioxidant level in smokers as compared to controls.
Authors and Affiliations
G D Dhokikar, P W Ingale, V H Birla
Keywords
Related Articles
- EP ID EP521696
- DOI 10.26611/1002922
- Views 139
- Downloads 0
Role of serum ferroxidase activity of ceruloplasmin in preeclampsia
Aim: To assess the role of ferroxidase activity of ceruloplasmin in women with preeclampsia. Materials and Methods: This study comprised of 40 preeclamptic cases and 40 age matched controls without having preeclampsia. R...
Correlation of Resistin levels with risk factors in type 2 diabetes mellitus patients with ischemic stroke
Background: Ischemic stroke in diabetic individuals is complex in nature with contributions from both environmental and genetic factors. Resistin links the metabolic dysregulation to atherosclerosis through selective inh...
A study of serum HDL with respect to exercise and vitamin B3 supplementation at tertiary health care centre
Background: Despite numerous therapeutic advances, cardiovascular disease (CVD) remains the leading cause of morbidity and mortality in world wide. Although statins reduce coronary artery disease by approximately 30% Aim...
Transfusion associated hemoglobinopathy
Transfusion associated hemoglobinopathy occurs when the donor is an asymptomatic carrier of the abnormal haemoglobin and such blood is transfused to a patient. Abnormal peaks are seen in High Performance Liquid Chromatog...
Apo A1/Msp1 polymorphismsin relation to Apo A-I and HDL-cholesterol levelin coronary artery disease patients with andwithout type II diabetes mellitus
A common Mspl polymorphism (G/A) in the promoter region of the APOAl gene (-75 bp) has been shown to be associated with plasma apo A-I and HDL-C variation in several, but not all, studies. Recently another Msp I polymorp...