A study of serum HDL with respect to exercise and vitamin B3 supplementation at tertiary health care centre
Journal Title: Medpulse International Journal of Biochemistry - Year 2019, Vol 9, Issue 2
Abstract
Background: Despite numerous therapeutic advances, cardiovascular disease (CVD) remains the leading cause of morbidity and mortality in world wide. Although statins reduce coronary artery disease by approximately 30% Aims and Objective: To study serum HDL with respect to exercise and vitamin B3 supplementation at tertiary health care centre. Methodology: This was a cross-sectional study carried out in the department of Medicine at tertiary health care centre during the one year period i.e. January 2017 to January 2018 in the patients who were having deranged lipid profile with HDL level low all the patients were prescribed exercises like walking at least for 45 min and at least 5 days in a week with oral supplementation of vitamin B3 with RDA (Recommended Daily Allowance) as a B-complex supplementation once in day for 6 weeks. The statistical analysis was done by unpaired t-test and calculated by SPSS 19 version software. Result: In our study we have seen that the majority of the patients were in the age group of 40-50 were 23.81%, followed by 30-40 were 22.22%, 20-30 were 19.05%, 50-60 were 20.63%, >60 were 14.29%. The majority of the patients were Male i.e. 61.90% and Female were 38.10%. At Baseline (n=63) the mean HDL-C level was (Mean±SD) - 32 ±3.45; 1month after intervention (n=61) - 33± 4.12 there was increase after 1 month but not statistically significant (t=1.4672, df = 122, p>0.05). 6 weeks after intervention (n=59) the mean HDL-C level was - 41.23 ± 3.42 which was significantly higher as compared to baseline level (* t=14.8294, df = 120, p< 0.0001) Conclusion: It can be concluded from our study that the B3 supplementation and exercise increased the HDL cholesterol level at one month but not statistically significant; at 6 week they significant statistically increased HDL-C level.
Authors and Affiliations
R Mohan Doss
Keywords
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