Study of liver and kidney function tests in patients of hypothyroidism
Journal Title: Medpulse International Journal of Biochemistry - Year 2017, Vol 4, Issue 2
Abstract
Background: In India, thyroid disorders are most common among all endocrine Disorders and hypothyroidism being more common than hyperthyroid state and carcinoma thyroid. Thyroid hormones regulate the basal metabolic rate of all cells, including liver and renal cells and in turn liver and kidney play an important role in thyroid hormones metabolism. So thyroid dysfunction may affect liver and kidney function and liver and kidney diseases may modulate thyroid hormone metabolism. So the present research was aimed to study the liver and kidney function tests in patients of hypothyroidism. Material and Methods: Thyroid hormones were measured by Minividas immunoanalyser. Biochemical parameters of liver and kidney function tests were estimated by kit method using Erba EM360 autoanalyser while serum electrolytes were estimated by ion selective electrodes. Results: Significant rise in biochemical parameters of LFT (ALT, AST) and biochemical parameters of KFT(Urea, creatinine, potassium) and significant decrease in sodium and chloride were observed in hypothyroid subjects (TSH >10 mIU/ml ) as compared to euthyroid subjects. Conclusion: Hyypothyroid patients should be regularly checked for biochemical parameters of LFT and KFT as early detection and treatment can prevent the further complications related to the disorder and will be helpful during the management of thyroid patients.
Authors and Affiliations
S S Bandebuche, S B Jagtap
Keywords
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