Duration of type 2 diabetes mellitus as a threat indicator for the microalbuminuria; A signal for diabetic nephropathy
Journal Title: Medpulse International Journal of Biochemistry - Year 2018, Vol 6, Issue 3
Abstract
Background: Diabetes mellitus is one of the major health problem leading to the long term kidney damage and responsible for 30-40% of all chronic kidney diseases. Aim and Objectives: The study was conducted to find the association of microalbuminuria in relevance to the duration of diabetes mellitus and HbA1c in a randomly selected type 2 diabetic patients. Material and Methods: The study was done from December 2012 to November 2013 in Raichur Institute of Medical Sciences, Karnataka. We have taken hundred type 2 diabetic cases based on history, clinical examination and related investigations. Result: Microalbuminuria contains a extremely significant correlation with the duration of diabetes (r = 0.81, p< 0.001) and HbA1c level (p = 0.001, r = 0.574). Conclusion: Relationship between microalbuminuria and the duration of diabetes mellitus shows more significant correlation compare to microalbuminuria and HbA1c level. The study has put light on the long term vulnerability of the high blood glucose as a risk for the accumulation of advanced glycosylation of end products which contribute the pathology to develop microalbuminuria rather than the HbA1c level alone. The present study emphasizes the need of regular screening for microalbuminuria and HbA1c, and can act as a risk indicator of diabetic nephropathy and early intervention to prevent complications.
Authors and Affiliations
Basavaraj Savadi, Archana H B
Keywords
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