Evaluation of Parasympathetic Activity by Heart Rate Variability in Gastroesophageal Reflux Disease Patients
Journal Title: Scholars Journal of Applied Medical Sciences - Year 2016, Vol 4, Issue 12
Abstract
The disturbed autonomic nervous system regulation may be responsible for functional lower esophageal sphincter failure,so the present study aimed to evaluate the parasympathetic activity in patients with Gastroesophageal reflux disease by time domain measures of Heart rate variability analysis. One hundred five subjects, which include Gastroesophageal reflux disease patients, thirty five each, aged 35-45 years (who presented typical symptom of Gastroesophageal reflux disease with reflux esophagitis (ERD) and without reflux esophagitis (NERD)) and thirty five age and sex matched control subjects, were evaluated in the study. Autonomic function test were assessed by using time domain measures of Heart rate variability. The findings of the present study showed highly significant (p < 0.001) reduced values of SDNN, RMSSD and pNN50 in patients withGastroesophageal reflux disease as compared to control subjects predicting reduced parasympathetic activity in patients with Gastroesophageal reflux disease.Disturbances in parasympathetic branch of autonomic nervous system affect both contraction and transient relaxation of the lower esophageal sphincter, leading to the occurrence and progression of Gastroesophageal reflux disease. Keywords:Autonomic Nervous System, Gastroesophageal reflux disease, Time domain measures, Heart rate variability analysis.
Authors and Affiliations
Teena Sogan, Manisha Sankhla, Keerti Mathur
Keywords
Related Articles
- EP ID EP371679
- DOI -
- Views 40
- Downloads 0
Age Determination Using Lateral Cephalogram and Orthopantomograph: A Comparative Study
Abstract: The identification of human skeletal remains is considered to be initial step in forensic investigation. Investigations of jaws and teeth, the most well preserved parts of human body have been proven a basic an...
Study to Find Out Incidence of Cardiac Manifestation in Thyroid Disorder (Hypo and Hyper Both)
Abstract: In summary out of 56 patients of thyroid dysfunction one patient did not have any symptoms suggesting cardiac involvement. 55 patients (98.2 %) had some kind of cardiac symptom. 51 patients (91.07%) had evidenc...
Surgical Management of Anterior Cruciate Ligament Injuries by Arthroscopic Reconstruction Using Semitendinosus and Gracilis Tendon
The unprecedented growth and development in the past decade of our country saw rapid growth and urbanization resulted in change in life style of the people and also increases in the sports and other occupational related...
Objective Structured Practical Examination (OSPE) as an Assessment Method of Laboratory Practical Skill Sessions in First MBBS Students of Biochemistry: A Research Study in SAIMS, Regional Centre of Medical Education, Indore
Abstract: OSPE act as a good tool to evaluate skill competency in Biochemistry subject. The first MBBS students admitted for 2014-16 batches of SAIMS, Indore were the subjects for the study. After successfully completing...
Perception about Penis Length, Penile Erection and Quantity of Semen among Young Adult Men of Pondicherry, India-Community Based Cross Sectional
Abstract: The psychological factors towards the perception of one own sexual organ is very important of the good sexual health in the era of widespread social networks and internet. The information on perception about pe...