Evaluation of performance of Lipid Accumulation Product (LAP), an obesity index as a marker for diagnosing overt type 2 diabetes mellitus over Body Mass Index (BMI)

Journal Title: International Journal of Clinical Biochemistry and Research - Year 2016, Vol 3, Issue 4

Abstract

Objectives of the study: To compare the indices available to measure obesity such as BMI and “lipid accumulation product” (LAP) with respect to risk for development of Type-II Diabetes mellitus. Methodology: The study design was cross sectional with sample size of 120. Anthropometric measurements (BMI and LAP) and biochemical estimations (blood glucose & lipid profile) were carried out. Results: We compared the values of LAP and BMI with Fasting blood glucose. The area under the curve was 0.75 and 0.73 respectively which meant LAP was better in identification of overt Type 2 Diabetes. The cut off for BMI is 25.98 with Sensitivity of 0.83, Specificity of 0.64 & youden index 0.47. The cut off for LAP is 50.79 with Sensitivity of 0.79, Specificity of 0.68 & youden index 0.46.

Authors and Affiliations

Nirmitha Dev. M, Krishnamurthy U

Keywords

Related Articles

Assessing the utility of serum Cholinesterase, Lactate dehydrogenase and Albumin/Globulin ratio in differentiating liver diseases

Introduction: Variety of liver diseases including alcoholic liver disease (ALD) is responsible for liver related morbidity and mortality in India. Distinguishing ALD from non-alcoholic steatohepatitis (NASH) and viral he...

Comparative study of glycoproteins in normal individuals and in patients with hypothyroidism and hyperthyroidism

Aim the present study was carried out to compare the glycoproteins in normal individuals and in patients with hypothyroidism and hyperthyroidismMaterials and Methods This study was carried out at Meenakshi Medical Colleg...

Biochemical markers of renal and hepatic function in gestational diabetes mellitus

Aim: To assess the biochemical parameters of renal and hepatic function in women with GDM and compare the results with those of normal pregnant women. Materials and Methods: Cases: The study group consisted of 45women wi...

Usefulness of gamma-glutamyl transpeptidase and mean corpuscular volume in alcoholic liver disease

Introduction Excessive consumption of alcohol and alcoholism are widely observed risk factors for damage to health and social problems Early identification of alcoholic liver disease could improve the possibility of earl...

Ferritin and vitamin b12 levels in patients with recurrent aphthous ulcers

Background: Recurrent aphthous ulcers (RAU) are one of the most common ulcerative lesions of the oral cavity with a prevalence rate of approximately 50-66%. The prevalence of hematinic deficiencies including ferritin and...

Download PDF file
  • EP ID EP243062
  • DOI -
  • Views 56
  • Downloads 0

How To Cite

Nirmitha Dev. M, Krishnamurthy U (2016). Evaluation of performance of Lipid Accumulation Product (LAP), an obesity index as a marker for diagnosing overt type 2 diabetes mellitus over Body Mass Index (BMI). International Journal of Clinical Biochemistry and Research, 3(4), 426-428. https://europub.co.uk/articles/-A-243062