EVALUATION OF PHYTOCHEMICALS AND ANTIOXIDANT ACTIVITY OF SEEDS USED IN TRADITIONAL MEDICINE
Journal Title: Journal of Drug Delivery and Therapeutics - Year 2014, Vol 4, Issue 5
Abstract
Phytochemicals are secondary metabolites of plants which are non-nutritive chemicals that have protective or disease preventive properties. It is well known that plants produce these metabolites to protect itself but recent research demonstrates that many phytochemicals can protect humans against diseases. The seeds of Cucumis sativus, Citrullus lanatus and Cucurbita pepo are used in herbal medicine as such or in the form of seed oil. They have various medicinal properties. Qualitative and quantitative analysis of phytochemicals and their antioxidative property is evaluated. Antioxidants are beneficial in oxidative stress related diseases. Acetone extracts of all the three seeds showed the presence of phenols, flavonoids and carbohydrates. Saponins, alkaloids, steroids, tannins and anthocyanins were absent in all the three extracts. Citrullus lanatus seeds with 7.5mg and 92.6mg GA equivalent/g of extract powder showed maximum amount of Phenolics and flavonoids. The total sugars and proanthocyanidins was maximum in Cucurbita pepo seeds with 3.6 µg glucose equivalent/g of extract powder and 171mg GA equivalent/g of extract powder. Citrullus lanatus seed extract showed the highest reducing power activity, Free radical scavenging potential and inhibition of lipid peroxidation.
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OVARIECTOMISED AND LONG TERM INDUCED (OLI) RAT MODEL FOR PRECLINICAL ASSESSMENT OF OSTEOPOROTIC THERAPEUTICS.
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INCREDIBLE TASTE MASKING OF CLARITHROMYCIN
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Current trends in drugs avoided in pregnancy
During pregnancy several drugs are having contraindication, hence their use is less and dangerous to mother along with fetus .Drugs play an important role in improving the health and promoting well-being. However to prod...
LIQUISOLID TECHNIQUE AS A PROMISING TOOL TO ENHANCE SOLUBILITY AND DISSOLUTION OF POORLY WATER SOLUBLE DRUG VALSARTAN
“Liquisolid Technique” considered as new technique to enhance solubility and dissolution rate of poorly water soluble drugs. These formulations are prepared by mixing drug in liquid state (solution, suspension or emulsio...