EVALUATION OF PLATELET COUNT AND PLATELET INDICES IN PATIENTS WITH ACUTE MALARIA IN SHENDI LOCALITY
Journal Title: Journal of Biomedical and Pharmaceutical Research - Year 2014, Vol 3, Issue 3
Abstract
Background: Malaria is the commonest cause of morbidity in Africa. This study describes altered platelet count and platelet indices in patients with acute malaria caused by Plasmodium falciparum, Plasmodium vivax and plasmodium malariae and uses these alterations as initial hint for malarial infection and therefore encourage the laboratory physicians for more depth search of the parasite microscopically. Methods: Platelet count and platelet indices in (123) patients with acute malaria were evaluated, living in Shendi locality in northern Sudan, an area of malarial holoendemic transmission. Results: The results of this study showed that platelet count, mean platelet volume (MPV), and Plateletcrit (PCT) values were exhibited significant decrease, but there was no change in platelet distribution width (PDW). Three sympatric Plasmodium species were recorded during this study with different prevalence of (77.2%) P.falciparum, (13.8%) P.malairae and (8.9%) P.vivax consequently. Mean platelet count decreased with an increase in density of parasitaemia. Conclusion: Malaria is associated with different degrees of reduction platelet count and alteration of platelet indices and may be used as probable indicator for malaria in endemic regions and therefore encourage the laboratory physicians for more depth search of the parasite microscopically.
Authors and Affiliations
Mohamed Abdelrahamn| Mohamed. S, PSC Medical Laboratory Science, Shendi University, Haematology Department. Shendi, Elfatih Mohammed| Elfatih. A, MSC Medical Laboratory Science, Shendi University, Haematology Department. Shendi, Abdelwahab Abdien| Abdelwahab. S, MSC Medical Laboratory Sciences, Shendi University, Clinical Chemistry Department. Shendi, Rashid Eltayeb| Rashid. E, MSC Medical Laboratory Sciences, Shendi University, Haematology Department. Shendi, Mohammed Osman| Mohammed. A, MSC Medical Laboratory Sciences, Shendi University, Haematology Department. Shendi
Keywords
Related Articles
- EP ID EP2520
- DOI -
- Views 314
- Downloads 17
TO STUDY SUSPECTED ADVERSE REACTIONS INCLUDING BIRTH DEFECTS IN PRIVATE APEX HEALTH CARE CENTRE (UTTAR PRADESH) INDIA.
According to the World Health Organization definition, this is any noxious, unintended, and undesired effect of a drug, which occurs at doses used in humans for prophylaxis, diagnosis, or therapy. This definition exclude...
SURGICAL RELEASE FOR TENNIS ELBOW-A CASE SERIES AT VIMS, BELLARY
OBJECTIVE: To assess the outcome of open release in the management of resistant tennis elbows, based on patient satisfaction. METHODS: This was an observational retrospective case series of 25 consecutive patients that u...
NATURAL COMPOUNDS IN BREAST DRUG DISCOVERY: IN SILICO FILTERING OF PLANT COMPOUNDS AS ANTICANCER AGENT WITH A SYSTEMATIC COMPUTATIONAL BACKGROUND.
Breast cancer is the most frequent cancer type and severe physical illness causing untold suffering to women. The inherited cases of breast cancer are due the occurrence of germ line mutation and rearrangement of the gen...
Therapeutic effect of quercetin on the complications of nicotinamide-streptozotocin induced type-2 diabetes in male rats
Introduction: Type-2 diabetes mellitus (T2DM) is a rapid growing epidemic disease, with a continually increasing prevalence that exhibit complications in different body organs. The nicotinamide-streptozotocin (NA-STZ) ra...
STUDIES ON AN AMIDE BASED MUTUAL PRODRUG: SYNTHESIS AND EVALUATION
The aim of this study has been to prepare a useful drug, which could have broad spectrum of antimicrobial activity including antitubercular action. Thus, an amide-based mutual prodrug (NA-INH) was synthesized by condensi...