Evaluation of Polyherbal formulation for Diuretic activity in albino rats
Journal Title: Asian Pacific Journal of Tropical Disease - Year 2012, Vol 2, Issue 0
Abstract
Objective: To investigate the diuretic potential of Polyherbal formulations prepared from the seeds of Vitis venifera, Duranta repens and Centratherum anthelminticum in Albino rats. Methods: Different concentrations of Polyherbal formulations (100, 200 and 400 mg/kg), furosemide (10 mg/kg) and vehicle were orally administered to rat (n = 6 animals per group) and their urine output was collected after 24h. The Urinary output, Osmolarity, pH, Na+, K+ and Cl- concentrations of urine were estimated. Results: The Polyherbal formulations produced significant increase in Na+, K+, Cl- excretion, caused alkalinization of urine, showed strong Diuretic index, saluretic index and Natruretic index. All the concentrations of Polyherbal formulation showed dosedependent relationship when compared to control animals. Conclusions: These finding strongly suggests that the Polyherbal formulations have a good diuretic activity on rats in the above experimental model.
Spatial and statistical analyses of the relations between vegetation cover and incidence of cutaneous leishmaniasis in an endemic province, northeast of Iran
Objective: To investigate the relations between the vegetation cover and occurrence of cutaneous leishmaniasis (CL) in Golestan province during 2010-2012. Methods: Data of monthly CL incidence and remote sensing normaliz...
Cardioprotective effect of Spathodea campanulata bark on isoproterenol-induced myocardial infarction in rats
Objective: To evaluate the cardioprotective potential of 70% ethanolic extract of bark of Spathodea campanulata P. Beauv (EEBSC). Methods: Wister strain rats were pretreated with EEBSC in two different doses (250 and 500...
Is the directly observed therapy short course (DOTS) an effective strategy for tuberculosis control in a developing country?
Objective: To investigate the effectiveness of the directly observed therapy short course (DOTS) strategy in tuberculosis control in developing countries. Methods: Secondary data was searched to identify relevant publica...
The effects of a social-cognitive method based education on knowledge and attitudes intentions with respect to HIV transmission among students in Maragheh, Iran
Objective: To evaluate a social-cognitive method based HIV/AIDS prevention education among students in high schools of a small city in Maragheh, Iran. Methods: The study was based on a pre-post-quasi experimental design;...
Profile of HIV infected children
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