Is the directly observed therapy short course (DOTS) an effective strategy for tuberculosis control in a developing country?
Journal Title: Asian Pacific Journal of Tropical Disease - Year 2013, Vol 3, Issue 3
Abstract
Objective: To investigate the effectiveness of the directly observed therapy short course (DOTS) strategy in tuberculosis control in developing countries. Methods: Secondary data was searched to identify relevant publications. Databases, organizational websites and search engines were utilized. Sort criteria were then applied to further limit the articles used. Results: A total of 50 articles were found. Abstracts of the 50 articles were then scrutinized and 26 that met the inclusion criteria were identified. Full length copies of these articles were obtained and analysed to extract salient details which were relevant to the research question. Conclusions: DOTS as a whole remains the cornerstone of tuberculosis control in developing countries. In the setting of high human immunodeficiency virus (HIV) infection rates and HIV/tuberculosis co-infection, there is a pressing need to modify DOTS to increase its relevance.
Surveillance of multidrug resistance of two Gram-positive pathogenic bacteria in a teaching hospital and in vitro efficacy of 30 ethnomedicinal plants used by an aborigine of India
Objective: To record hospital- and community-acquired accounts of multidrug resistance (MDR) of two Gram-positive pathogens, Staphylococcus aureus (S. aureus) and Enterococcus faecalis (E. faecalis), by surveillance, and...
Study of the inhibition effect of ethanolic extract of mangosteen pericarp on atherogenesis in hypercholesterolemic rat
Objective: To investigate the effect of ethanolic extract of mangosteen pericarp (EEMP) through lipid profile, H2O2, nuclear factor-kappa B (NF-κB), inducible nitric oxide synthase (iNOS) and endothelial nitric oxide syn...
Profile of seizures in adult falciparum malaria and the clinical efficacy of phenytoin sodium for control of seizures
Objective: To study the profile of convulsion in adult severe falciparum malaria and efficacy of phenytoin sodium for its control. Methods: It comprised of two sub studies. Study-1 evaluated the pattern and risk factors...
Dangers of injections overuse in developing countries with a high HIV/ AIDS prevalence: a review on HIV risk hazards, traumatic effects and other blood borne infections
Use of injections is commonly practiced in both developed and developing countries. However, in developing countries like Tanzania, both public and private health care providers prescribe and administer injections to cli...
HPTLC fingerprint profile of Bauhinia variegata Linn. leaves
Objective: To develop the finger print of medicinally and economically important leaves of Bauhinia variegata Linn. Methods: Ethanol extract of the leaves were developed in the mobile phase of n-Hexane: Ethyl acetate: Fo...