Evaluation of safety and efficacy with propofol and etomidate for induction of Anaesthesia in dilatation and curettage
Journal Title: Indian Journal of Clinical Anaesthesia - Year 2018, Vol 5, Issue 4
Abstract
Introduction and Aims We compared the safety efficacy hemodynamic variation recovery duration and adverse effects of propofol and etomidate with or without fentanyl in patients undergoing dilatation and curettage for incomplete abortionsMaterials and Methods One hundred patients ASA status I II aged 2050 years undergoing dilatation and curettage were randomly divided into four groups of 25 patients each Group P received propofol 2 mgkg normal saline 2 ml for anesthesia induction Group PF received propofol 2 mgkg fentanyl 1mcgkg to make volume 2 ml for anesthesia induction Group E received etomidate 02 mgkg normal saline 2 ml for anesthesia induction and Group EF received etomidate 02 mgkg fentanyl 1 mcgkg to make volume 2 ml for anesthesia induction Heart rate arterial pressure and SpO2 were recorded at different time intervals The recovery time pain on injection myoclonus and postoperative nausea vomiting were also recordedResults During induction mean arterial pressure fall significantly in both propofol groups Amongst four groups there was no significant difference observed in recovery time after anesthesia The incidence of pain on injection was lower in etomidate groups Myoclonus and Postoperative nausea and vomiting were significantly higher in etomidate groupsConclusion This study demonstrates that etomidate is superior in term of hemodynamic stability and less incidence of pain on injection Etomidate combined with low dose fentanyl is more favourable than etomidate alone for attenuating myoclonusKeywords Etomidate Dilatation and curettage Propofol
Authors and Affiliations
Archana Tripathi, Seema Meena, Mukesh Somvanshi, Surendra Kumar
Keywords
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- EP ID EP476475
- DOI 10.18231/2394-4994.2018.0091
- Views 82
- Downloads 0
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