Low dose ketamine pretreatment for alleviation of propofol injection pain- A study
Journal Title: Indian Journal of Clinical Anaesthesia - Year 2018, Vol 5, Issue 2
Abstract
Introduction One of the most important disadvantages of propofol injection is intense burning pain The present study was conducted with the aim to assess the effect of low dose Ketamine 100 gkg in the alleviation of pain on propofol injectionMaterials and Methods Patients who underwent surgical procedures under general anaesthesia were allocated into two groups viz Group K n35 pretreatment with ketamine 100gkg 1ml and Group S n35 pretreatment with 09 normal saline 1ml in this doubleblinded randomized study After venous occlusion ketamine was injected over 10 seconds after which the occlusion was removed and over 20 seconds the first 25 of the calculated dose of propofol was injected The evaluation of the severity of pain was done by the verbal rating scale VRS during the injection of the induction agent for every 5 seconds and graded as 0 to 3The data were recorded and analysedusing unpairedt test and chisquare test as and where appropriateResults The demographic profiles were comparable between the two groups It was observed that 429 of patients in normal saline and 80 in ketamine groups experienced no pain p005Conclusion It may be concluded that pretreatment with low dose ketamine with a tourniquet just before propofol injection significantly reduced the incidence and degree of propofol induced pain without significant adverse hemodynamic effectsKeywords Induction Propofol Pain Low dose ketamine Alleviation
Authors and Affiliations
Yamini Taloh, Nongthombam Ratan Singh, Mumtak Borang, Praneshwari Sinam, J. F. Pyngrope
Keywords
Related Articles
- EP ID EP476444
- DOI 10.18231/2394-4994.2018.0031
- Views 75
- Downloads 0
Comparison of orotracheal versus nasotracheal fibreoptic intubation in simulated cervical spine patients, under conscious sedation
Introduction and Aims Airway management in a patient with cervical spine injury is considered a challenge Minimizing neck movement and maintaining head in neutral position is essential to prevent secondary neurological i...
A comparison of intrathecal Dexmeditomidine and Buprenorphine as an adjuvants to isobaric spinal 0.75% Ropivacaine in patients undergoing elective lower limb surgery
Introduction: Ropivacaine is the single enantiomer specific local anaesthetic having reduced potential for cardiotoxicity and neurotoxicity. Its characteristics of slow onset, shorter duration of sensory analgesia and ra...
Comparative study of bupivacaine with dexmedetomidine and only bupivacaine during brachial plexus block
Introduction: Regional anaesthesia techniques are very successful in alleviating pain during and after various surgical procedures. During upper extremity surgery Supraclavicular Brachial plexus block is commonly adminis...
Acute Fatty Liver of Pregnancy: Case series report
Acute fatty liver of pregnancy, a rare clinical entity demands early diagnosis, immediate delivery of fetus, systematic approach for correction of coagulopathy, renal injury & sepsis along with hemodynamic and ventilator...
Post intubation high airway pressure’s: An uncommon case of kinked tube
High airway pressures post intubation is a critical event which requires the urgent intervention of the attending anesthesiologist We report a case of high peak pressure and plateau pressure after intubation which was ac...