Evaluation of screening methods for the students who had close contact with pulmonary tuberculosis patients in Shanghai
Journal Title: Shanghai Journal of Preventive Medicine - Year 2023, Vol 35, Issue 3
Abstract
ObjectiveTo evaluate the current screening methods for the students who were in close contact with tuberculosis patientsï¼ that could accurately identify the preventive treatment subjectsï¼ and to improve the tuberculosis prevention and control in Shanghai schools.MethodsThe freshman/sophomore who were in close contact with active tuberculosis patients in the colleges in 2019 were recruited. All the subjects underwent both tuberculin skin test ï¼TSTï¼ and QuantiFERON-TB gold in-tube ï¼QFTï¼ test at the enrollment. After signed the informed consentï¼ all of the participants filled in a questionnaire and determined their baseline tuberculosis infection status. They were followed up for 2 years to monitor the conversion of infection status and the incidence of tuberculosis.ResultsFour of 9 ï¼44.4%ï¼ positive participants had conversion to negative resultsï¼ and 5 of 300 ï¼1.7%ï¼ negative participants had conversion to positive during the 2-year follow-upï¼ one of which was diagnosed with active tuberculosis. We assessed diagnostic agreement between QFT and TST at different cut-off values. The highest coincidence rate was 94.0% when choosing 15 mm as the cut-off valueï¼ with Kappa coefficient of 0.45 ï¼95%CIï¼ 0.32â0.59ï¼.ConclusionAlthough stricter than the national work requirementsï¼ the prevention and control of tuberculosis in Shanghai schools still need to be carried out meticulously. It's necessary to strengthen daily prevention and control measuresï¼ and improve the ability of management.
Authors and Affiliations
XIAO Xiao,CHEN Jing,SHEN Xin,
Keywords
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