Evaluation of Serum Lactate as Predictor of Morbidity and Mortality in Sepsis and Trauma Cases
Journal Title: IOSR Journal of Pharmacy and Biological Sciences (IOSR-JPBS) - Year 2017, Vol 12, Issue 3
Abstract
Background and objectives:Utility of serial serum lactate measurement to find patients in occult hypotension and its use in treating critically ill patients. Design:Prospective non interventional observation study in RGGGH. Method:50 patients admitted with either trauma or suspected sepsis, whose icu stay is more than 48 hours, were followed till mortality or icu stay >7 daya or <7 days. Serial serum lactate measured at 0th ,12th ,24th, 36th hour in all 50 patients. Serum lactate level and the patient outcome were compared. Result:Serum lactate at zero hour (p=0.000), 12th hour(p=0.000), 24th hour(p=0.000) and 36th hour(p=0.000) were statistically more accurate in predicting the outcome of the critically ill patient. Serum lactate is an individual prognostic factor and is useful to identify sick patients early, before MODS sets in.
Authors and Affiliations
1Dr. S . Umarani, 2, Dr. Iyyappa Arumugam, Dr. Anand Prasath Jayachandiran
Keywords
Related Articles
- EP ID EP389802
- DOI 10.9790/3008-1203070105
- Views 78
- Downloads 0
Antilactogennic Characteristics Of Methanol Extract Of Aframomum Melegueta Seed In Wistar Rats.
This study was designed to investigate antilactogenic characteristics of methanol extract of Aframomum melegueta seed by measuring serum concentrations of lactogenic (prolactin, estradiol and progesterone) hormones in la...
A New Dammarane Triterpenoid Compound Isolated From Ixora Finlaysoniana
The air-dried leaves of Ixora finlaysoniana Wall. ex. Don ( family Rubiaceae) afforded a new dammarane triterpenoid named: 17β-dammara-1-one -20 ene-3β-3', 8'-dimethyloctanoate (1) together with two known saturated fatty...
Association between Testosterone and Prostate Cancer among SudanesePatients in Khartoum State
Background: Prostate is a compound tubuloalveolar exocrine gland of the male reproductive system in most mammals. It considers differ among species anatomically chemically and physiologically. Prostate cancer also known...
Review: Immobilization and application of lipase
Immobilized enzymes are more robust and more resistant to environmental changes than free enzymes in solution. Enzyme immobilization provides an excellent base for increasing availability of enzyme to the substrate with...
Validated Reverse Phase Stability-Indicating Hplc Method for Clofarabine in the Presence of Degradation Products and its Process-Related Impurities.
The study reports simultaneous determination of clofarabine and its related substances of impurities in their pharmaceutical dosage form using validated stability indicating reverse phase high performance liquid chromato...