Evaluation of Sonographic Detected Fatty Livers: Comparison of Multi Parametric MRI with ARFI Elastography; An Initial Experience
Journal Title: Journal of Advances in Medicine and Medical Research - Year 2017, Vol 23, Issue 10
Abstract
Background: Even as ultrasound based elastography detects changes in liver stiffness with good accuracy newer emerging tools using magnetic resonance imaging(MRI) are being evaluated to have a global assessment of Non alcoholic fatty liver disease(NAFLD). This study was designed to compare the role Multiparametric MRI (mpMRI) and ultrasound elastography in the assessment of fatty liver detected on sonogram. Study: 50 consecutive non alcoholic patients with no prior history of chronic liver disease with fatty liver on sonogram had shear wave elastography using acoustic radiation force impulse (SW-ARFI) imaging followed by Mp MRI. The median liver stiffness was assessed on ARFI while liver fat content, iron content along with Mean T1 value of liver determined on MpMRI. The results of both modalities were statistically analyzed. Results: Out of 50 patients examined with echogenic fatty livers, 30 were males and 20 females with mean age of 42 years. The median liver stiffness on ARFI was 1.37 m/s while median T1 on Mp MRI was 653.8 msec. MpMRI showed a sensitivity and specificity of 100%, 91% in detection of liver inflammation with AUC of 1.0 with ARFI. Statistically significant linear relationship was seen between liver iron content and liver fat content in all groups with T1 maps. 3 patients had abnormal high liver iron content with normal liver fat content but had echogenic fatty liver appearance on ultrasound. Conclusion: Mp MRI detects changes in liver stiffness based on T1 estimation of liver parenchyma with high sensitivity and specificity with results comparable with SWI-ARFI. It has advantage over ARFI being more robust and also estimates liver fat and iron content and can be used a single shot test for comprehensive evaluation of echogenic livers.
Authors and Affiliations
Atul Kapur, Goldaa Mahajan, Aprajita Kapur, J S. Sidhu
Keywords
Related Articles
- EP ID EP312446
- DOI 10.9734/JAMMR/2017/36343
- Views 57
- Downloads 0
A Review of Experimental Studies for Available Evidence on the Use of Prosthetic Material in Hiatal Hernia Repair
Aim: The benefits of prosthetic material in hiatal hernia repair have been well documented. However, the associated risks are substantial and they are related to the technique, and also the choice of material. Experiment...
Bromocresol Dye-binding Methods Underestimate Serum Albumin Value in Patients Treated with High Dose of Penicillin G
Background: Various factors contribute to the discrepancies observed between the bromocresol green (BCG) and bromocresol purple (BCP) assays of serum concentration. Either a BCG or a modified BCP assay is a routine labor...
Differences and Relationships between Morphometric Parameters and Zinc Content in Nonhyperplastic and Hyperplastic Prostate Glands
Aims: To clarify the changes in morphometric parameters and contents of zinc (Zn) and in the relationship between these characteristics in normal and hyperplastic human prostates, a quantitative morphometry and energy-di...
The Implementation of an Effective Aerobic Walking Program Based on Ottawa Panel Guidelines for Older Individuals with Mild to Moderate Osteoarthritis: A Participant Exercise Preference Pilot Randomized Clinical Trial Protocol Design
Aims: Osteoarthritis is the most common disabling disorder affecting particularly knees. A recent systematic review demonstrated the efficacy of walking programs for improving pain, functional status, endurance, and qual...
Common Infectious Etiologies of Acute Febrile Illness in a Remote Geographical Location: Could Scrub Typhus be the Most Common Cause?
Background: Disease burden of acute febrile illness due to infectious etiologies is under reported in various parts of India including Sikkim due to lack of laboratory confirmation. Undifferentiated febrile illnesses com...