EVALUATION OF SYMPATHETIC DOMINANCE BY AUTONOMIC FUNCTION TESTS IN CHILDREN OF HYPERTENSIVE PARENTS
Journal Title: Journal of Evolution of Medical and Dental Sciences - Year 2017, Vol 6, Issue 63
Abstract
BACKGROUND Hypertension is a global problem. Positive family history of hypertension is one of the risk factors for being hypertensive in future life for their children. Hyperactive sympathetic nervous system is reported in children of hypertensive parents. Aim- The main aim of the study was to observe the magnitude of alterations in autonomic reactivity in normotensive male offsprings of both hypertensive and normotensive parents. MATERIALS AND METHODS Fifty young and healthy male subjects between 19-24 years of age got examined for autonomic reactivity. Twenty-five of them were having positive family history (cases) while the remaining children were having negative family history (control group) of hypertension. Non-invasive autonomic function tests as per Ewing’s criteria were performed in all the subjects and study group compared with cases. RESULTS The resting heart rate, systolic and diastolic blood pressures were not significantly raised in subjects of study group. The sympathetic function tests as assessed by rise in diastolic blood pressure following cold pressor test and handgrip test were highly significant in study group as compared with control one. However, parasympathetic functions were similar in both groups. CONCLUSION It seems that there is increased sympathetic activity in children of hypertensive parents which may predispose them to hypertension in their later life.
Authors and Affiliations
Ajay Kumar, Sonu Ajmani
Keywords
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- EP ID EP231434
- DOI 10.14260/Jemds/2017/990
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