Evaluation of the Antibacterial and Antifungal Activity of Three Retrograde Filling Materials: An In Vitro Study
Journal Title: International Journal of Contemporary Medical Research - Year 2016, Vol 3, Issue 8
Abstract
Introduction: Retrograde filling materials are used with the purpose of obtaining root end sealing in the endodontic surgeries. In addition to improving the sealing of the existing root canal filling, these materials should possess antimicrobial properties to prevent the movement of bacteria and their products from the root canal system to the periapical tissues for the success of the endodontic surgeries. Study aimed to evaluate the antibacterial and antifungal properties of mineral trioxide aggregate (MTA) compared to biodentine and resin modified glass ionomer cement (RMGIC). Material and methods: Pellets of MTA, Biodentine and RMGIC were prepared to test the influence of these cements on the growth of strains of Enterococcus faecalis, Staphylococcus aureus and Candida albicans using the agar diffusion method. Wells were formed by removing agar and the test materials were manipulated and placed in the wells. The growth inhibition diameter around each material against the tested organism was measured after 24 hour incubation at 37o C. The data was analysed statistically using analysis of variance (ANOVA) and unpaired t-test to compare the differences among the three cements. Results: Inhibition zones for Biodentine against E.faecalis and C.albicans significantly larger (P<0.01) when compared to MTA and RMGIC. However RMGIC showed significantly larger (P<0.01) zone of inhibition against S.aureus but no zone of inhibition against C.albicans. Conclusion: All materials showed antimicrobial activity against the tested strains except RMGIC against C.albicans. Biodentine had a greater antimicrobial activity compared to MTA and RMGIC.
Authors and Affiliations
Meghna S. Chopra, Meenal N. Gulve
Keywords
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