EVALUATION OF THE EFFECTS OF CAPSULES CONTAINING TRIBULUS TERRESTRIS EXTRACT AND LCARNITINE ON TREATMENT OF OLIGOSPERMIA IN MALES
Journal Title: Journal of Evolution of Medical and Dental Sciences - Year 2018, Vol 7, Issue 29
Abstract
BACKGROUND Infertility is defined as failure to achieve pregnancy after one year of unprotected sexual intercourse. Male infertility is one of the most challenging problems in andrology. The common cause of male infertility is related to disorders in sperm production. In this study for the first time, effect of combination Tribulus terrestris extract and L-carnitine on sperm parameters of infertile men were reviewed. MATERIALS AND METHODS This double-blind study was conducted on 61 men, 25 to 40 years old with infertility due to sperm abnormalities on semen analysis parameters (Criteria WHO). They were randomly assigned to two groups of 350 mg herbal capsules containing Tribulus terrestris extract + L-carnitine (Intervention) or 350 mg placebo capsules (Control) 4 times a day for 3 months. At the beginning and end of the study, semen analysis and serum levels of FSH, LH and testosterone were evaluated, and results were compared between the groups with baseline. RESULTS The results showed that after three months of intervention in control group, no significant change in semen analysis parameters and levels of FSH, LH and testosterone happened (p>0.5). In the intervention group, only Progressive index in semen analysis (28.6 vs 33.2) from baseline showed statistically significant changes (p=0.033). The difference of efficacy between intervention and control groups before and after the study was not significant in any of the parameters. CONCLUSION Based on the results of this study, treatment with herbal capsule containing Tribulus terrestris extract and L-carnitine for three months in the improvement of abnormal sperm parameters in infertile men is not effective.
Authors and Affiliations
Mahmoudi Hossein, Akbari Hossein, Taghizade Mohsen, Jahangirian Jamileh, Mohboobi Mohadese, Mahlooji Mahnaz
Keywords
Related Articles
- EP ID EP538307
- DOI 10.14260/jemds/2018/736
- Views 98
- Downloads 0
A RETROSPECTIVE DESCRIPTIVE STUDY OF HEAD INJURY PATIENTS ADMITTED IN MY HOSPITAL, INDORE, BETWEEN 2011-2013
BACKGROUND Traumatic brain injury is an alarming and rising epidemic disease affecting the majority of population of Indore. A detailed epidemiological study was therefore much needed to analyse its impact on the health...
EVALUATION OF ERECTILE DYSFUNCTION WITH DUPLEX COLOUR DOPPLER SONOGRAPHY OF PATIENTS PRESENTING IN IGIMS, PATNA
BACKGROUND Duplex colour Doppler sonography is a useful tool for the evaluation of erectile dysfunction, especially for organic causes like arterial and venous. The causes of erectile dysfunction are multiple. It could b...
EXPRESSION OF SURVIVIN AND p53 IN BREAST CANCER
BACKGROUND Survivin, a novel inhibitor of apoptosis, that inhibits caspases and blocks cell death, is highly expressed in most cancers. Many studies have indicated that aberrant expression of Survivin is associated with...
FRUITFULNESS OF RAJIV GANDHI JIVANDAYI YOJANA TO PATIENTS OF END-STAGE KIDNEY DISEASE TAKING DIALYSIS
BACKGROUND In recent era, incidence of CKD is increasing. Despite of it, very few patients seek Renal Replacement Therapy in India due to very high costs. Recently, Govt. of India has launched Rajiv Gandhi Jivandayi Yoja...
ISCHAEMIC STROKE IN YOUNG WOMAN DUE TO PROTEIN-C DEFICIENCY
PRESENTATION OF CASE A 30-year-old previously healthy female patient was admitted in this teaching hospital with history of sudden onset of sensory loss and weakness of left upper and lower limbs. She had headache for 10...