Evaluation of the efficiency of the various techniques used for screening of HIV in antenatal mothers to facilitate early initiation of treatment
Journal Title: IP International Journal of Medical Microbiology and Tropical Diseases - Year 2018, Vol 4, Issue 3
Abstract
The study has been conducted in pregnant women in the high risk category attending the antenatal OP at MNR Hospital and medical college and Niloufer Hospital for a defined period The screening tests for HIV used are Coombaids Dot Immunoassay as per NACO guidelines Fourth Generation double antigenantibody Sandwich with solid micro wells precoated with Recombinant HIV1gp41 HIV1 Group O gp41 HIV2 gp36 amp Monoclonal Anti p24 Antibodies The individual sensitivity and specificity were evaluated and compared The sera of all the women screened by COOMBAIDS were tested negative out of all the negative samples one sample was tested positive by 4th generation ELISA Hence this study was carried out to evaluate the sensitivity and specificity of various techniques for Antibody detection and Antigen detection and to determine the technique most suitable for early diagnosis of HIV infection4Keyword Antenatal women Specificity and Sensitivity
Authors and Affiliations
Kola Sujatha, ML Kavitha
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