Urinary E.coli isolates in tertiary care centre of south Kerala: Antibiogram and ESBL detection by phenotypic confirmatory disc diffusion testing
Journal Title: IP International Journal of Medical Microbiology and Tropical Diseases - Year 2018, Vol 4, Issue 4
Abstract
Gram negative bacterial infections are the most important cause of Urinary Tract Infections UTI in India Ecoli being the most common isolate and has been resistant to commonly used antibioticsMaterials and Methods This study was done to assess the antibiotic sensitivity pattern of uropathogenic Ecoli and to detect Extendedspectrum lactamase E coli isolated from samples collected in patients with urinary tract infections Antibiotic sensitivity pattern was assessed using CLSI 2017 guidelines ESBL detection was carried out using phenotypic Confirmatory Disc Diffusion TestResults 87 Ecoli isolates were collected from urinary samples during the study period Antibiotic sensitivity profiles showed that uropathogenic Ecoli were sensitive to Amikacin Gentamicin PiperacillinTazobactum Tetracyclines Nitrofurantoin Carbapenams Ecoli exhibited resistance to cephalosprins and Fluroquinolones 50 strains among the 87 isolates showed ESBL production by Phenotypic Confirmation Disc Diffusion Test PCDDTDiscussion Ecoli has established itself as a strong uropathogen Ecoli infections are more common in females due to anatomical factors Most of the uncomplicated urinary tract infections happen in females of child bearing age group There is an urgent need for the formulation of antibiotic policy for initiation of presumptive treatment The way forward to handle antibiotic resistance is implementation of safe hands policy with handwashing well informed usage of antibiotics for an appropriate duration along with implementation of universally accepted infection control protocolsKeywords Antibiotic policy Antibiotic resistance PCDDT Uropathogenic Ecoli Urinary Tract Infection
Authors and Affiliations
Prasobh KK. , Riyaz Sheriff, Jesna Johnson, Lakshmi Sarayu
Keywords
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- EP ID EP485881
- DOI 10.18231/2581-4761.2018.0048
- Views 74
- Downloads 0
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