The study of inducible clindamycin resistance and antimicrobial susceptibility pattern of the Staphylococcus aureus isolates from various clinical samples
Journal Title: IP International Journal of Medical Microbiology and Tropical Diseases - Year 2018, Vol 4, Issue 1
Abstract
Introduction Staphylococcus aureus is responsible for skin and soft tissue infections surgical site infections Macrolidelincosamidestreptogramin B MLSB antibiotics particularly clindamycin is favoured agent to treat skin and soft tissue infections cause by Staphylococcus aureus Broad utilization of these antibiotics has prompted an expansion in resistance against these antimicrobials requiring the need to recognize such resistance on routine premise utilizing a D testAims and Objectives To study inducible clindamycin resistance amp antimicrobial susceptibility pattern of S aureus isolatesMaterials and Methods 300 isolates of S aureus from different clinical examples were subjected to antimicrobial susceptibility testing by Kirby Bauers disc diffusion method Just erythromycin resistant isolates were subjected for D test to contemplate inducible clindamycin resistance according to CLSI guidelinesResults Out of 300 isolates 171 57 S aureus isolates were erythromycin resistant Among these isolates 84 28 showed MS phenotype 68 2266 showed inducible resistance amp 19 633 showed constitutive resistanceConclusion A D test can be utilized to identify inducible clindamycin resistance This test will help for legitimate treatment of the patients yet additionally counteract misuse of antimicrobial agentsKeywords Staphylococcus aureus D test Inducible clindamycin resistance Erythromycin
Authors and Affiliations
T. R. Patil, S. V. Wankhede
Keywords
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- EP ID EP485826
- DOI 10.18231/2455-6807.2018.0001
- Views 77
- Downloads 0
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