Antibiotic profile of enterobacter isolates from various clinical samples – A study from a tertiary care hospital
Journal Title: IP International Journal of Medical Microbiology and Tropical Diseases - Year 2018, Vol 4, Issue 4
Abstract
Introduction Enterobacter species especially Enterobacter cloacae are important nosocomial pathogens They cause infections of the lower respiratory tract skin soft tissue urinary tract and occasionally sepsis Enterobacter species are often seen in natural habitats like water and soil Enterobacter species are often resistant to various antibiotics in a hospital setting Resistance to antimicrobials can also develop during therapy The emergence of antimicrobial resistance especially to third generation cephalosporins is a concern in the management of Enterobacter infectionsObjectives To evaluate the antimicrobial resistance pattern of Enterobacter species isolated from patients attending a tertiary care hospitalMaterials and Methods The present study was conducted in the Microbiology department of a tertiary care hospital The study was conducted from January 2012 to December 2012 Enterobacter species were isolated from the clinical samples of patients using standard microbiological methods of bacterial culture and identification Antibiotic susceptibility testing was done by KirbyBauer disc diffusion method according to Clinical laboratory standard institute CLSI guidelines Minimum inhibitory concentration MIC of cefotaxime was determined by the microbroth dilution methodResults During the study period 100 isolates of Enterobacter species were isolated from clinical samples The predominant species of Enterobacterisolated was Enterobacter cloacae69 followed by Enterobacter aerogenes 25 Antibiotic susceptibility testing showed that most of the isolates were resistant to ampicillin 86 The resistance to cefotaxime was 33Conclusion Enterobacter species in a tertiary care setting could be resistant to common antibiotics like ampicillin and cephalosporins Clinicians should be aware of these resistance pattern while choosing an empiric antibiotic regimenKeywords Enterobacter species Enterobacter cloacae Enterobacter aerogenes Antimicrobial resistance pattern cephalosporin resistance
Authors and Affiliations
Smitha Rockey, Vinay Kumar
Keywords
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- EP ID EP485883
- DOI 10.18231/2581-4761.2018.0050
- Views 94
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