Isolation & study of multidrug resistant Acinetobacter from various clinical samples in a tertiary care hospital
Journal Title: IP International Journal of Medical Microbiology and Tropical Diseases - Year 2016, Vol 2, Issue 2
Abstract
Introduction: Nosocomial infections with Acinetobacter are being increasingly reported worldwide from debilitated& Critical care patients. Multidrug resistance among Acinetobacter are now a major cause of concern. So the study was conducted to know prevalence & antimicrobial resistance pattern of Acinetobacter species in our area. Materials & Methods: A total of 100 non-duplicate clinical specimens were processed for Acinetobacter by the routine microbiological procedures. Antimicrobial susceptibility testing was performed as per CLSI guidelines. Result: Acinetobacter species were isolated from 9% of clinical samples. The higher percentage of isolates were from Pus 7(20%) followed by urine 1(4%) and 1(3%) from Blood. We found Highest isolates were from ICU -7(77.78%) followed by wards 2(22.22%). No isolates were found from Outpatient (OPD). 77% of our isolates showed resistance to drugs piperacillin-tazobactam and ceftriaxone while lower resistance was noted to ciprofloxacin &tetracyclines (33% respectively). Resistance pattern for other drugs was co-trimaxazole (66%), gentamycin & piperacillin (55% respectively), amikacin, ofloxacin & imepenem - 44%. Interesting finding in our study was 11% of our isolated were sensitive to all the tested antimicrobials whereas 22% isolates were resistant to all the tested antimicrobials. Conclusion: 22% of our isolates showed resistant to all the tested antimicrobials. Thus judicial use of antimicrobials & adopting strict infection control policies will be useful.
Authors and Affiliations
S. V. Wankhede, D. P. Ghadage2, T. R. Patil, A. V. Bhore
Keywords
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