Evaluation of the possibility of horizontal gene transfer and accumulation of transgenic DNA from the diet in the bodies of rats
Journal Title: Journal of Animal and Feed Sciences - Year 2010, Vol 19, Issue 2
Abstract
The procedures for GMO safety tests include traceability of transgenic protein and transgenic DNA if the plant constitutes a component in the diet for an animal. This is due to the possibility of horizontal transfer of genes, accumulation of transgenic DNA in consumer’s organs, or induction of antibiotic resistance in gastrointestinal tract microflora. The last possibility is related to the use of marker genes in the process of transformation. In an in vivo experiment conducted on laboratory rats with the use of transgenic cucumbers expressing the pre-prothaumatin gene, the presence of transgenic DNA in the tissue of kidneys and liver was not detected. Resistance to neomycin of gastrointestinal tract microflora of the rats fed the GMO diet was not found, despite the use of marker genes (npt II) in the process of transformation of the investigated plants.
Authors and Affiliations
I. Kosieradzka, V. Vasko, A. Przybysz, Sz. Fiedorowicz, M. Szwacka
Keywords
Related Articles
- EP ID EP73707
- DOI -
- Views 115
- Downloads 0
Gas production kinetics in predictions of voluntary intake of grass silage by cattle
The objective of this study was to predict voluntary intake by cattle of grass silages of different fermentation quality from in vitro gas production data. Further, biological concepts of intake related gas data were exa...
The effects of adding lucerne protein concentrate to diets on the reproductive traits and blood metabolic profiles of sows and piglets
The aim of the study was to estimate the effects of supplementing different amounts of lucerne protein concentrate (LPC) on performance, blood haematological and biochemical parameters of sows and their offspring. LPC wa...
The use of genetically modified Roundup Ready soyabean meal and genetically modified MON 810 maize in broiler chicken diets. Part 2. Functional status of the small intestine
The effects of genetically modified (GM) soyabean meal (SBM) and GM maize on the functional status of the small intestine of broiler chickens was studied. Eight diets were prepared, based on conventional or GM SBM (GTS 4...
Genetic evaluation of the growth of beef bulls at a performance test station
Genetic evaluation of the growth of bulls at a performance test station was performed using a single-trait model (STAM) and multi-trait models that included pre-weaning growth. The growth of the bulls was represented by...
The influence of dietary fatty acids on their metabolism in liver and subcutaneous fat in growing pigs
The aim of the study was to determine the influence of fatty acids sources on their metabolism in the liver and subcutaneous fat. Four iso-energetic and iso-protein diets with different ratio of PUFA/SFA and C 18:2 n-6/C...