Evaluation of the survival rate and its related factors in patients with leukemia in Kurdistan Province
Journal Title: مجله علمي دانشگاه علوم پزشكي كردستان - Year 2018, Vol 23, Issue 94
Abstract
Background and Aim: In recent decades, the survival rates of the children with cancer have improved significantly and their five-year survival rates have reached 80%, but there are still many concerns about the survival of adolescents and young people. Methods and Materials: In this retrospective study, the data of 310 children and adults with leukemia in Kurdistan Province were extracted from their medical records. Univariate and multivariate survival analysis were performed through calculating hazard ratios using Cox relative risk model. Data analysis was carried out using Stata 12 software. Results: This study included 201 adults with mean age of 50.8 years and 109 children with mean age of 5.2 years. The frequency of AML was higher in the adults (30.8%), while the frequency of ALL cases was higher in the children (86.2%). The respective one-year and five-year survival rates, were 94.4% and 49.5% in the adults, and 92.6% and 83% in the children. The hazard ratios (HR) were 5.18 (95% CI: 2.60-13) in the adults with ALL and 4.11 (95% CI: 1.55-10.4) in the adults with AML, and 2.78 (95% CI: 1.05-7.37) in the patients with CML. Based on the results of multivariate analysis, the rate of mortality in children with ALL was lower (HR=0.26, 95% CI: 0.08-0.77). Conclusion: Timely diagnosis and provision of treatment services for the patients are recommended. Considering the high rate of survival in the patients with ALL especially in children, we recommend provision of appropriate treatment facilities and palliative care services, similar to those in other countries, for the patients with different types of leukemia with high rates of mortality.
Authors and Affiliations
MD, PhD Gh Moradi, MSc M. A Rasouli, Medical Student F Fathi, MD B Ghaderi, PhD D Roshani, MD J Soltani
Keywords
Related Articles
- EP ID EP291424
- DOI -
- Views 68
- Downloads 0
Prevalence of non-communicable diseases risk factors among the population of rural areas of Kurdistan Province, in Iran: A population-based study by rapid assessment method in 2015
Background and Aim: Determination of prevalence of non-communicable diseases (NCD) risk factors is the key factor for designing any intervention program for the control and prevention of these diseases. The aim of this s...
Mycobacterium gordonae pulmonary infection with clinical manifestations similar to tuberculosis
Background and Aim: Mycobacterium gordonae is one of the most important human mycobacterial pathogens that is found in immuno-compromised patients and also healthy people. This study is the first case report of Mycobacte...
The effect of vitamin D supplementation during resistance training on the markers of systemic inflammation in untrained males
Background and Aim: Physical activity has a dual effect on inflammation. Different studies have showed very contradictory results. The present study was designed to investigate the effects of vitamin D supplementation du...
Ovarian torsion in a heterotopic pregnancy: a case report
Background and Aim: Ovarian torsion is one of the rare causes of emergency surgeries during pregnancy. Heterotopic pregnancy is a rare type of pregnancy characterized by embryo implantation in two different locations. oc...
The effect of proprioceptive neuromuscular facilities (PNF) stretching exercise on patellofemoral pain syndrome (PFPS)
Background and Aim: Patellofemoral pain syndrome (PFPS) is a common disorder of the knee. the conservative treatment of patellofemoral pain syndrome is to correct shortness of soft tissue. The aim of this study was to d...