Evaluation of the survival rate and its related factors in patients with leukemia in Kurdistan Province
Journal Title: مجله علمي دانشگاه علوم پزشكي كردستان - Year 2018, Vol 23, Issue 94
Abstract
Background and Aim: In recent decades, the survival rates of the children with cancer have improved significantly and their five-year survival rates have reached 80%, but there are still many concerns about the survival of adolescents and young people. Methods and Materials: In this retrospective study, the data of 310 children and adults with leukemia in Kurdistan Province were extracted from their medical records. Univariate and multivariate survival analysis were performed through calculating hazard ratios using Cox relative risk model. Data analysis was carried out using Stata 12 software. Results: This study included 201 adults with mean age of 50.8 years and 109 children with mean age of 5.2 years. The frequency of AML was higher in the adults (30.8%), while the frequency of ALL cases was higher in the children (86.2%). The respective one-year and five-year survival rates, were 94.4% and 49.5% in the adults, and 92.6% and 83% in the children. The hazard ratios (HR) were 5.18 (95% CI: 2.60-13) in the adults with ALL and 4.11 (95% CI: 1.55-10.4) in the adults with AML, and 2.78 (95% CI: 1.05-7.37) in the patients with CML. Based on the results of multivariate analysis, the rate of mortality in children with ALL was lower (HR=0.26, 95% CI: 0.08-0.77). Conclusion: Timely diagnosis and provision of treatment services for the patients are recommended. Considering the high rate of survival in the patients with ALL especially in children, we recommend provision of appropriate treatment facilities and palliative care services, similar to those in other countries, for the patients with different types of leukemia with high rates of mortality.
Authors and Affiliations
MD, PhD Gh Moradi, MSc M. A Rasouli, Medical Student F Fathi, MD B Ghaderi, PhD D Roshani, MD J Soltani
Keywords
Related Articles
- EP ID EP291424
- DOI -
- Views 66
- Downloads 0
Mycobacterium gordonae pulmonary infection with clinical manifestations similar to tuberculosis
Background and Aim: Mycobacterium gordonae is one of the most important human mycobacterial pathogens that is found in immuno-compromised patients and also healthy people. This study is the first case report of Mycobacte...
The effects of local heat therapy in the posterior part of chest on physiologic parameters in the patients with acute coronary syndrome: a randomized double-blind placebo-controlled clinical trial
Background and Aim: Treatment and management of the symptoms of acute coronary syndrome (ACS) are very important. Pharmacological and non-pharmacological measures have been used for the relief of symptoms in these patien...
Effect of prenatal immobilization stress on spatial memory, anxiety-like behavior and brain BDNF concentration in the F1 generation male mice
Background and Aim: In this study, we investigated the effect of immobilization stress during pregnancy on the spatial memory, anxiety-like behavior and brain BDNF level in F1 generation male NMRI mice. Materials and Met...
Nurses’ mental health in Iran: A national survey in teaching hospitals
Background and Aim: Mental health disorders are common problems among health care professionals such as nurses, which can create great problems .The aim of this study was to evaluate mental health status in nursing perso...
Investigation of the factors related to low birth weight in the south of Iran: a case-control study
Background and Aim: Since birth weight is one of the most important health indicators, we decided to investigate the factors related to the low birth weight (LBW) of the infants in the south of Kerman Province. Material...