Evaluation of various factors influencing sputum smear positivity in newly diagnosed cases of pulmonary tuberculosis at a tertiary care centre of Bengaluru
Journal Title: IP Indian Journal of Immunology and Respiratory Medicine - Year 2018, Vol 3, Issue 3
Abstract
Introduction In a developing country like India tuberculosis TB is a common infectious disease diagnosed both in rural and in urban population According to WHO world health organisation an open case of tuberculosis has at least three close contacts in their household resulting in prevalence rate of 25 among the close contacts In the developing country it adds on to the economic burden Many factors have been attributed to persistence of sputum positivity even at the end of intensive phase of TB treatmentObjective We conducted a retrospective study at our institution to identify the clinical radiological and bacteriological factors of the patients influencing sputum conversion for AFB acid fast bacilli at the end of intensive phase 2 months of anti tubercular treatment in category 1Material and Methods A retrospective Study was conducted at our institution from January 2016 to December 2017 Newly diagnosed open cases of TB were included in the study with retro viral cases being excluded from the studyResults Out of 179 cases in the study 103 cases were male and 86 cases were females The predictive analysis and chi square test showed statistically significant association of smoking cavity formation and degree of bacillary load and persistent sputum positivityConclusion Smoking cavity formation and higher ABF load in the initial smears have higher possibility of persistent sputum positivity requiring more vigilant monitoring of such patientsKeywords Tuberculosis Sputum positivity Smoking Cavity formation Bacillary load
Authors and Affiliations
Saroja B. G.
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