Evaluation ofEosinophil count and Hemoglobin concentration inpetrol pump workers in Allahabad
Journal Title: GJRA-Global Journal For Research Analysis - Year 2015, Vol 4, Issue 6
Abstract
IntroductionIt is world known fact that petrochemical workers are exposed to many noxious substances present in the work places. The most untoward effects are due to Benzene which is present in the petrol and being volatile substance it is present in the atmosphere nearbyBenzene is an organic chemical compound with molecular formula C6H6. It is a well known carcinogen with relative hematotoxicity ObjectiveThus the objective of this study is to find out the effect of benzene exposure on hematological parameter especially Eosinophil count and Hemoglobin concentration on petrol pump workers. Material and MethodSixty petrol pump workers healthy male nonsmokers, matching between age group of 20-60 years were included in this study. The forty not exposed to any type of air pollutants were enrolled as control subjects are included in the study.Blood samples were analyzed by automated hematological analyzer for hemoglobin concentration white blood cell count including count of Eosinophil. ResultAnthropometric parameter of study group and control group are statistically non-significant (p >0.05).The Eosinophil count in study group and control groupin subjects exposed to more than 15 years the count was significantly (<0.05) decreasesHemoglobin concentration non-Significant in all stage. Discussion The petrol pump workers under high risk of benzene may cause bone marrow depression, hematological and neurological toxic effect and cancer.In the present study Eosinophil count and Hemoglobin concentration taken as marker of benzene toxicity. Other study also support our study like T. Tunsaringkarnet.al. ConclusionThe Eosinophil count decreases as the duration of exposure increases, because long term exposure to benzene causes bonemarrow suppression leads to decreased Eosinophil count.
Authors and Affiliations
Narendra Gupta, RajBahadur Kamal, Richa Singh
Keywords
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