Evaluaton of hypoglycaemic and wound healing activities of Tiliacora acuminata
Journal Title: Indian Journal of Pharmaceutical and Biological Research - Year 2014, Vol 2, Issue 4
Abstract
Natural products particularly plant origin have played a vital role in prevention and mitigation of human diseases. The present study was carried to evaluate the antihyperglycaemic and wound healing activity of the leaf Extracts of Tiliacora acuminate (Lam) on rats, the aqueous leaf extract was found to produce significant reduction of blood glucose concentration between 2-4 h of administration in alloxan induced hyperglycaemic rats at tested dose levels. However, in normoglycaemic animals, the extract at 400mg/kg produced significant reduction of blood glucose between 2-4 h of administration. In the wound healing studies, the leaf juice was found to be more active than the extract.
Authors and Affiliations
Ram Mohan Manda| Department of Pharmacognosy&Phytochemistry, TallaPadmavathi College of Pharmacy, Warangal-506002, Telangana, India, Vishwanath valusa| Department of Pharmacognosy&Phytochemistry, TallaPadmavathi College of Pharmacy, Warangal-506002, Telangana, India, Srinivas Reddy Karka| Department of Pharmacognosy&Phytochemistry, Vaagdevi College of pharmacy, warangal, Telangana, India, Vamshi Krishna Parshaboina| Department of Pharmacognosy&Phytochemistry, Vaagdevi College of pharmacy, warangal, Telangana, India, Ganapaty Seru| GITAM Institute of Pharmacy, GITAM University, Gandhi Nagar, Visakhapatnam-530 045, Andhra Pradesh, India
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