Evalution of anti-HAV antibodies (IgM) among children aged 1-5 years in Diyala governorate
Journal Title: IOSR Journal of Pharmacy and Biological Sciences (IOSR-JPBS) - Year 2018, Vol 13, Issue 4
Abstract
With improvement in economic and living conditions of the communities, the age of acquiring hepatitis A virus (HAV) infection is shifting from early childhood to adolescence and young adulthood. Such epidemiological shift leads to an increased incidence of symptomatic HAV infection, including heightened risk of liver failure.The present study was conducted in Diayala province for the period from 15 / 10 / 2017 to 10 / 4 / 2018. It included; 80 children patients were attended Al-Batool Hospital. 19 of patients were males and 61 were females. The age range was 1 years to 5 years. The study aimed to determining the rate of HAV-specific IgM antibodies in children aged from1 to 5 years. Serum specimens were collected for each children. Detection of HAV-specific IgM was done by Enzyme Rapid test. The results of the present study showed that the 9 children (11.25%) were anti-HAV IgM positive and 71 (88.75%) were anti-HAV IgM negative. There was higher seropositivity of HAV between age group (1-2) years (23.07%) for anti-HAV IgM with other age groups. In this study regarding gender, the rapid test positivity rate was in females (4.91%) was lower than that in males (31.57%). In conclusion, am recommended that working similar studies need to be done in other parts of the Diayla governorate. Additionally, the present study recommended that Hepatitis A virus vaccination should be considered carefully in Iraq and other developing countries, because of the high seropositivity to HAV in our region.
Authors and Affiliations
Ansam Dawod Salman, Zainab Amer, Shyamaa Mohammed
Keywords
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- EP ID EP395459
- DOI 10.9790/3008-1304010912
- Views 76
- Downloads 0
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