EVALUTION OF ANTIASTHMATIC ACTIVITY OF CALOTROPIS GIGANTEA ROOTS
Journal Title: Int J of Pharm Rev& Res - Year 2013, Vol 3, Issue 2
Abstract
The present study deals with the effect of ethanolic extract of roots Calotropis gigantea by using various in vivo and in vitro animal models. In vitro model like isolated guinea pig ileum preparation was studies to know basic mechanism by which extract shows relaxant activity. The study shows that extract is effective against histamine induced contraction. Animal studies involve use of histamine induced bronchocontraction. These studies showed significant protection at lower doses while further increase in dose level showed reduced activity. The results of these studies indicated usefulness of ethanol extract of Calotropis gigantean in asthma.
Authors and Affiliations
Pramod Patil*
Keywords
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