EVALUTION OF ANTIASTHMATIC ACTIVITY OF CALOTROPIS GIGANTEA ROOTS
Journal Title: Int J of Pharm Rev& Res - Year 2013, Vol 3, Issue 2
Abstract
The present study deals with the effect of ethanolic extract of roots Calotropis gigantea by using various in vivo and in vitro animal models. In vitro model like isolated guinea pig ileum preparation was studies to know basic mechanism by which extract shows relaxant activity. The study shows that extract is effective against histamine induced contraction. Animal studies involve use of histamine induced bronchocontraction. These studies showed significant protection at lower doses while further increase in dose level showed reduced activity. The results of these studies indicated usefulness of ethanol extract of Calotropis gigantean in asthma.
Authors and Affiliations
Pramod Patil*
Keywords
Related Articles
- EP ID EP138284
- DOI -
- Views 129
- Downloads 1
DESIGN AND DEVELOPMENT OF MEBEVERINE COMPRESSION COATED TABLETS FOR COLONIC DELIVERY
The main objective of this study was to develop mebeverine hydrochloride colon targeted drug delivery system using compression coating technique for effective treatment of irritable bowel syndrome. This work was mainly f...
PRESCRIBING PATTERN OF DRUGS IN PEDIATRIC WARDS AT A TERTIARY CARE TEACHING HOSPITAL
Pediatrics differs from adult medicine in many respects. Inappropriate prescribing is a recognized worldwide problem of the health care delivery system. Antibiotics are the widely used drugs in modern medical care. A pro...
PEDIATRIC DOSAGE FORM -CHALLENGE FOR PHARMACEUTICAL INDUSTRY
ABSTRACT Despite the fact that a significant percentage of the population is unable to swallow tablets and capsules, these dosage forms continue to be the default standard. These oral formulations fail many patie...
NATURAL PRODUCTS BOTACHEMICAL POTENTIALITY AND HEALTH PERSPECTIVES
It‟s well established that oxygen is essential for survival and energy generation in all-living organisms and ~5% of its inhaled part is converted into free radicals (either ROS or RNS) as a by-product of aerobic metabol...
OCCURRENCE AND ANTIFUNGAL SUSCEPTIBILITY PATTERN OF CANDIDURIA ISOLATES AMONG DIABETIC PATIENTS
Diabetic patients are considered as the most vulnerable group for various infections; high level of sugar in blood and urine invites most pathogen to reside within the body and thus cause infection. Urinary Tract Infecti...