Evolution of sinonasal radiological findings in a case of granulomatosis with polyangiitis
Journal Title: Romanian Journal of Rhinology - Year 2019, Vol 9, Issue 33
Abstract
Wegener’s granulomatosis (Granulomatosis with Polyangiitis) is an autoimmune granulomatous disorder of unknown etiology. The basic pathology is necrotizing granulomatous inflammation with necrotizing vasculitis involving medium-sized blood vessels. The typical triad of involvement of the upper and lower respiratory tracts and the kidneys is observed in varying proportions in individual patients. The sinonasal involvement is observed in the majority of patients and it can be involved in isolation in up to a quarter of affected individuals. The sinonasal changes involve both the soft tissue and bony architecture, with refractory chronic sinusitis associated with erosion of the cartilaginous and bony skeleton and may lead to saddle nose and other facial deformities in advanced cases. The radiology has a contributory role as diagnostic and diseases monitoring aid. The various radiological findings associated with the disease (bone erosion with osteoneogenesis) have been mentioned in the literature. We present the progression of a radiological abnormality in a patient with a localized form of Wegener’s Granulomatosis and highlight some peculiar appearances observed on radiology in the patient.
Authors and Affiliations
Aru Chhabra Handa, Anup Singh, Jai Prakash Sharma
Keywords
Related Articles
- EP ID EP479900
- DOI 10.2478/rjr-2019-0006
- Views 90
- Downloads 0
Juvenile nasopharyngeal angiofibroma – literature review and case series
Juvenile nasopharyngeal angiofibroma is a rare benign tumour of vascular origin found in adolescent males, originating around the sphenopalatine foramen. Although the exact pathogenesis of the tumour is not yet known, na...
Anatomic patterns of maxillary sinus drainage
BACKGROUND. Functional endoscopic sinus surgery may be indicated when certain anatomic variations impede the normal drainage of the paranasal sinuses through the ostiomeatal complex. We aimed at studying the drainage sys...
Hereditary angioedema - an otolaryngologist’s perspective
Hereditary angioedema (HAE) is a rare autosomal dominant disease consisting of recurrent angioedema attacks, varying in severity, possibly life-threatening and with frequent involvement of the head and neck areas. The pa...
Preliminary outcomes in transcutaneous neuromuscular electrical stimulation use in patients with dysphagia
Dysphagia is a common disorder associated with a large number of etiologies like aging, stroke, traumatic brain injury, head and neck cancer, neurodegenerative disorders, structural changes or congenital abnormalities. T...
Complex facial reconstruction after removal of giant nasal ulcerated acantholytic squamous carcinoma
BACKGROUND. Excision of facial cutaneous carcinomas requires further reconstruction in a combined team with plastic surgeons. Among the traditional risk factors, the unprotected occupational exposure to sunlight can be i...