Juvenile nasopharyngeal angiofibroma – literature review and case series

Journal Title: Romanian Journal of Rhinology - Year 2018, Vol 8, Issue 29

Abstract

Juvenile nasopharyngeal angiofibroma is a rare benign tumour of vascular origin found in adolescent males, originating around the sphenopalatine foramen. Although the exact pathogenesis of the tumour is not yet known, natural history and growth patterns can be predicted. JNA progressively involves the nasopharynx, nasal cavity, paranasal sinuses, pterygopalatine fossa, infratemporal fossa and, in severe cases, an orbital or intracranial extension can be seen. Early diagnosis based on clinical examination and imaging is mandatory to ensure the best resectability of the tumour, as small to moderate tumours can be managed exclusively endoscopically. Preoperative angiography can reveal the vascular sources and allow embolization to prevent significant bleeding. We present a brief literature review followed by our case series of endoscopic removal of 7 juvenile nasopharyngeal angiofibromas.

Authors and Affiliations

Alexis Vuzitas, Claudiu Manea

Keywords

Related Articles

Frontal sinus osteoma

Frontal sinus osteoma

Possible association between -954G/C iNOS polymorphism in nasal polyposis. A case-control study in a population group of Northern Romania

BACKGROUND. Polymorphisms for genes encoding chemosensitive signalling proteins like NOS2 might contribute to the variability in individual susceptibility to nasal polyposis. NO produced by the inducible NO synthase enzy...

Evolution of sinonasal radiological findings in a case of granulomatosis with polyangiitis

Wegener’s granulomatosis (Granulomatosis with Polyangiitis) is an autoimmune granulomatous disorder of unknown etiology. The basic pathology is necrotizing granulomatous inflammation with necrotizing vasculitis involving...

Romanian ENT residency program - expectations and real facts

Romanian ENT residency program - expectations and real facts

Misdiagnosis of laryngeal sarcomatoid squamous cell carcinoma – case report

Background. Even if it is a rare variant growth pattern of squamous cell carcinoma, sarcomatoid carcinoma seems to have almost the same clinical manifestations and risk factors as conventional squamous cell carcinoma. Ca...

Download PDF file
  • EP ID EP265859
  • DOI 10.2478/rjr-2018-0002
  • Views 102
  • Downloads 0

How To Cite

Alexis Vuzitas, Claudiu Manea (2018). Juvenile nasopharyngeal angiofibroma – literature review and case series. Romanian Journal of Rhinology, 8(29), 17-24. https://europub.co.uk/articles/-A-265859