Ewing sarcoma of proximal tibial epiphysis: An unusual presentation with review of literature
Journal Title: Indian Journal of Pathology and Oncology - Year 2018, Vol 5, Issue 2
Abstract
Ewingrsquos sarcomaPrimitive neuroectodermal tumor ESPNET of bone is a rare childhood tumor most commonly located in the metadiaphysis It is more commonly seen in the appendicular skeleton and typically involves femur tibia humerus or fibula Within the long bones the tumor is always metaphyseal or diaphyseal middiaphysis 33 metadiaphysis 44 metaphyseal 15 Rarely 12 of ES may involve epiphysis In skeletally immature patients lesions of the epiphysis are rarely malignant with the most common diagnosis benign chondroblastoma We report a case of ES of the tibial epiphysis in a 16 year old boy presenting with complaints of pain around right knee joint for six months associated with fever and restricted mobility of knee joint Magnetic resonance imaging MRI of the patientrsquos right knee revealed a large lesion in the centre of upper tibial epiphysis showing hypointense signal on T1 amp T2W1 extending from the articular surface through the epiphyseal plate into the upper metaphyseal region MRI findings suggested an infective pathology with differential diagnosis of Brodiersquos abscess and chondroblastoma Based on the imaging characteristics the patientrsquos age and the lesionrsquos location a preliminary diagnosis of chondroblastoma was made Debridement and curettage of the lesion was performed and sent for histopathological examination Microscopy and subsequent immunohistochemistry confirmed it to be a case of ES An extensive research of literature was done and very few reports Of ES at epiphyseal location were found which make our case worth reporting This case highlights the rarity of epiphyseally located Ewing sarcoma cases and thus suggesting that the diagnosis of ES should also be considered for pediatric epiphyseal tumorsKeywords Ewing tumor Primitive neuroectodermal tumor Metadiaphysis Epiphysis Metaphyseal Chondroblastoma
Authors and Affiliations
Ruchi Sinha, Iffat Jamal, Amar Kumar, Anup Kumar
Study of Leukopenia as haematological parameter, to find it’s diagnostic rationale in dengue patients
Introduction The dengue fever is in the form of epidemic in India which occurs usually after rainy season There is need of adjuvant haematological parameters that can at very initial stage differentiate the dengue fever...
Intraoperative frozen section consultation- an audit in a tertiary care hospital
Introduction Frozen section FS helps the surgeon in the surgical management of the patient by helping in the intraoperative diagnosis of tumors margins and lymphnode assessment and organ identification Audits of the froz...
Study of transfusion transmitted infections among blood donors in a Tertiary care Hospital in Puducherry
Introduction: Transfusion of blood and its components is a life-saving procedure as even a unit of blood can save a patient in need. Though it is said to be a safe procedure as the blood is tested and processed before it...
Clinical and histopathological study of oral cancers in a tertiary care hospital, Tumakuru
India is a country where chewing pan, beetle-areca with lime is common among all age group. External and local irritation of buccal mucosa is associated with high risk of cancer. It may begin as a local lesion or by meta...
Utility of British Thy system of reporting Thyroid FNAC smears in a tertiary hospital
Introduction: Thyroid Fine Needle Aspiration (FNA) has been widely used as a first line investigation to assess thyroid nodules, as it is rapid, cost effective, safe and reliable. Thyroid cytology categories are required...