Excitatory amino acids and rheumatoid diseases

Journal Title: Reumatologia - Year 2005, Vol 43, Issue 6

Abstract

Excitatory amino acid (EAA), glutamate is a major neurotransmitter in the central nervous system. Its role in the periphery remains mostly unknown. Recently, EAA receptors there found on peripheral sensory terminals and dorsal root ganglion cells implicating their involvement in sensory and nociceptive transduction. The involvement of EAA mechanisms in inflammation was also suggested. It can be speculated that the use of EAA antagonists may provide a novel alternative for pharmacological intervention in joint inflammation and pain.

Authors and Affiliations

Jolanta Parada-Turska

Keywords

Related Articles

Chorobowość szpitalna spowodowana chorobami układu ruchu w województwie śląskim w latach 1999–2003

Cel: Celem pracy było przedstawienie zakresu hospitalizacji z powodu chorób układu ruchu w województwie śląskim w latach 1999–2003 i porównanie obecnej analizy z badaniem wcześniejszym, z lat 1980–1993, obejmującym cał...

Synovial fluid surface tension in inflammatory joint diseases

Surface tension (ST), free energy measure in surface layer, results from molecules interactions. Its value is influenced by every macro- and micromolecular substances present in solution, particularly surface active comp...

Antineutrophil cytoplasmic antibodies (ANCA)

The immunological characteristics and method of ANCA testing were presented in the paper. Author shows connection between ANCA and vasculitis, especially with Wegener`s granulomatosis, and clinical significance of ANCA...

The role of the regional anaesthesia performed for orthopaedic procedures in patients with rheumatic diseases

The aim of this work was to estimate the role of regional anesthesia for orthopaedic surgery. 719 patients with rheumatoid arthritis or osteoarthritis who underwent orthopaedic procedures in 2004 were included to study...

Sarcoidosis

Sarcoidosis is a systemic disorder of unknown origin. It is characterized by a noncaseating granulomatous. Many organs can be affected, but the most frequently lungs (almost 90% cases of sarcoidosis). The other organs: l...

Download PDF file
  • EP ID EP82319
  • DOI -
  • Views 97
  • Downloads 0

How To Cite

Jolanta Parada-Turska (2005). Excitatory amino acids and rheumatoid diseases. Reumatologia, 43(6), 349-353. https://europub.co.uk/articles/-A-82319