Experience in the diagnosis and treatment of Guillain — Barre syndrome with different clinical course

Abstract

Four clinical cases of Guillain — Barre syndrome were analyzed in two women and two men who were under thew treatment in hospital. In the first two cases, a rather short course of treatment (2 weeks) was associated with the general moderate condition of patients, who experienced motor and sensory disturbances in the limbs. Complaints of weakness in the limbs, impaired walking arose gradually and the patients did not visit the neurologist immediately. In these cases electroneuromyographic research was decisive for the diagnosis. In two cases, the disease developed after viral infections, in one case, it was against the background of injury and following surgery, in the other case, the etiology was not determined. The third and fourth cases had a severe course. Complaints involving cranial innervation were typical, in particular, a violation of swallowing. The severity of the condition quickly increased, with the development of peripheral tetraparesis to tetraplegia and the ineffectiveness of external respiration. The state of consciousness of the patients was almost not disturbed and, even with a massive lesion of the cranial nerves, the patients were accessible to the contact through the saved movements with their eyes, fingers or toes. Use of human immunoglobulin in the form of Bioven is the most accessible method of treatment in our conditions. The drug should be administered in the early stages of the disease. Inpatient treatment of severe cases lasted more than 3 months. In addition to mechanical ventilation, the decisive for a positive prognosis were massage, changing the position of the body every 1 — 2 hours, exercise therapy, speech therapist, myostimulation, amplipulse. Psychotherapy was extremely important: fighting depression, supporting and creating positive patient motivation.

Authors and Affiliations

G.  G. Simonenko, O.  E. Domoratskyi, M.  O. Stefaniuk, L.  V. Dubinina, R.  A. Mokrynskyi

Keywords

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  • EP ID EP670813
  • DOI 10.30978/UNJ2019-2-66
  • Views 133
  • Downloads 0

How To Cite

G.  G. Simonenko, O.  E. Domoratskyi, M.  O. Stefaniuk, L.  V. Dubinina, R.  A. Mokrynskyi (2019). Experience in the diagnosis and treatment of Guillain — Barre syndrome with different clinical course. Український неврологічний журнал, 0(2), 66-73. https://europub.co.uk/articles/-A-670813