Experience in the diagnosis and treatment of Guillain — Barre syndrome with different clinical course
Journal Title: Український неврологічний журнал - Year 2019, Vol 0, Issue 2
Abstract
Four clinical cases of Guillain — Barre syndrome were analyzed in two women and two men who were under thew treatment in hospital. In the first two cases, a rather short course of treatment (2 weeks) was associated with the general moderate condition of patients, who experienced motor and sensory disturbances in the limbs. Complaints of weakness in the limbs, impaired walking arose gradually and the patients did not visit the neurologist immediately. In these cases electroneuromyographic research was decisive for the diagnosis. In two cases, the disease developed after viral infections, in one case, it was against the background of injury and following surgery, in the other case, the etiology was not determined. The third and fourth cases had a severe course. Complaints involving cranial innervation were typical, in particular, a violation of swallowing. The severity of the condition quickly increased, with the development of peripheral tetraparesis to tetraplegia and the ineffectiveness of external respiration. The state of consciousness of the patients was almost not disturbed and, even with a massive lesion of the cranial nerves, the patients were accessible to the contact through the saved movements with their eyes, fingers or toes. Use of human immunoglobulin in the form of Bioven is the most accessible method of treatment in our conditions. The drug should be administered in the early stages of the disease. Inpatient treatment of severe cases lasted more than 3 months. In addition to mechanical ventilation, the decisive for a positive prognosis were massage, changing the position of the body every 1 — 2 hours, exercise therapy, speech therapist, myostimulation, amplipulse. Psychotherapy was extremely important: fighting depression, supporting and creating positive patient motivation.
Authors and Affiliations
G. G. Simonenko, O. E. Domoratskyi, M. O. Stefaniuk, L. V. Dubinina, R. A. Mokrynskyi
Keywords
Related Articles
- EP ID EP670813
- DOI 10.30978/UNJ2019-2-66
- Views 130
- Downloads 0
Clinical case of ischemic stroke development associated with nonspecific aortoarteritis (Takayasu disease)
The article describes a clinical case of development of ischemic stroke in the carotid and vertebrobasilar basin associated with nonspecific aortoarteritis (Takayasu disease). The diagnosis is confirmed by magnetic reson...
Nervous system impairment under systemic lupus erythematosus: pathogenesis aspects, prevalence and views on clinical manifestations classification
Systemic lupus erythematosus is an autoimmune disease that involves almost all organ systems. The nervous system in this case is not an exception, which is confirmed by the high prevalence of neurological symptoms in pat...
Possibilities and prospects of the application of the in vivo and in vitro toxic cuprizone model for demyelination in experimental and clinical neurology (literature review and own research results)
In this article, literature data and research findings obtained from the Experimental modeling laboratory of Institute of Genetic and Regenerative medicine are shown. This review testifies the effectiveness of using the...
The role of gut microbiota and nutrition features in the pathogenesis of multiple sclerosis and its course
The study of the role of microbiota in the pathogenesis of autoimmune and demyelinating diseases is of a particular importance. Experimental data obtained during the last 10 years shows a close connection between the imm...
Myotonic dystrophy. Clinical case
The article presents modern issues on etiopathogenesis, classification, typical clinical signs, diagnostic algorithm and treatment approaches for myotonic dystrophy. The actual clinical case is described in the article.