Experimental Vein Graft Research: A Critical Appraisal of Models
Journal Title: Heart Research – Open Journal - Year 2015, Vol 2, Issue 2
Abstract
Experimental models of vein grafting need to have specific relevance to the clinical complications encountered in coronary artery bypass grafting: acute thrombosis, neointima associated stenosis, and progression of late-forming atherosclerotic lesions. Despite extensive use, many of these experimental models lack endpoint measures with clear analogies to their clinical counterparts and may in fact target the wrong (patho) physiologic process. Model selection is critical to further progress toward preventing these all too prevalent complications used for heart revascularization.
Authors and Affiliations
Brian C. Cooley
Keywords
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- EP ID EP556811
- DOI 10.17140/HROJ-2-110
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