Expert consensus on testing of killer-cell immunoglobulin-like receptor genes
Journal Title: Chinese Journal of Blood Transfusion - Year 2023, Vol 36, Issue 7
Abstract
The killer-cell immunoglobulin-like receptor(KIR) gene family exhibits complex genetic diversity. In addition to allele level polymorphisms, KIR genes show extra diversity at haplotype content as well as copy number variation. In order to standardize the KIR gene testing, the Working Party on Histocompatibility, Chinese Society of Blood Transfusion (CSBT)and Shenzhen Blood Center organized experts to discuss and reach a consensus on KIR gene testing based on KIR-related literature and practical experience. The present consensus has summarized the techniques for identifying the diversity of KIR genes, quality control, testing report and its applications, aiming to improve the accuracy of KIR gene testing results.
Authors and Affiliations
Working Party on Histocompatibility, Chinese Society of Blood Transfusion (CSBT), Shenzhen Blood Center
Keywords
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- EP ID EP738580
- DOI 10.13303/j.cjbt.issn.1004-549x.2023.07.001
- Views 26
- Downloads 0
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