Expert consensus on the clinical application of niacin skin flush detection in psychiatry-Expert consensus of CSNP psychiatric disorders research alliance (2024 edition)
Journal Title: Chinese Journal of Nervous and Mental Diseases - Year 2024, Vol 50, Issue 11
Abstract
Attenuated niacin skin response is a known biological endophenotype of psychotic disorders. By measuring the degree of erythema induced by niacin, about 30% of psychiatric disorders can be identified as having this characteristic, which may be related to the pathophysiological mechanisms of phospholipid-inflammatory imbalance. This detection provides new prevention and treatment strategies for clinicians. To further promote the clinical application and operational standards of this technique, the Chinese Society of Neuroscience & Psychiatry (CSNP) Psychotic Disorders Research Alliance discussed and formulated the “Expert Consensus on the Clinical Application of Niacin Skin Response Detection in Psychiatry”. This consensus delved into the physiological mechanisms of niacin skin reactions, their abnormal mechanisms associated with psychotic disorders, detection methods, defining criteria, evidence as biomarkers for psychotic disorders, auxiliary diagnostic value, and clinical intervention measures. Expert recommendations were formulated regarding the necessity of this detection, its scope of application, standardization of procedures, interpretation of results, targeted interventions, and its value in early screening and prevention.
Authors and Affiliations
Chinese Society of Neuroscience & Psychiatry (CSNP) Psychiatric Disorders Research Alliance.
Keywords
Related Articles
- EP ID EP759205
- DOI 10.3969/j.issn.1002-0152.2024.11.001
- Views 25
- Downloads 0
One case of adult onset neuronal nuclear inclusion body disease
This article reports a case of adult neuronal intranuclear inclusion body disease with clinical manifestations of tremor, cognitive decline, and binocular visual impairment, which has not been clearly diagnosed and treat...
Comparative study on the predictive abilities of multiple inflammatory markers for the poor outcome of intracerebral hemorrhage
[Objective] This study aimed to investigate the relationship between multiple inflammatory markers and poor outcome in patients with intracerebral hemorrhage, and to compare their predictive abilities. [Methods] We retro...
Investigating the distant thalamic and substantia nigra damage in patients with cerebral infarction based on voxel morphology analysis
[Objective] To explore the clinical values of voxel-based morphometry (VBM) analysis in magnetic resonance imaging (MRI) for detecting secondary damage to the distant thalamus and substantia nigra in patients with cerebr...
Establishment of stable Schwann cell lines with genetic intervention of MST2 and its appliance in the detection of mitochondrial membrane potential
[Objective] To construct rat Schwann cell RSC96 cell lines that stably knock down or overexpress mammalian ste20-like kinase 2 (MST2), and preliminarily explore its regulatory effect on mitochondrial membrane potential....
Analysis of the current status and countermeasures for diagnosis and treatment in the epilepsy specialty clinic at a single-center comprehensive hospital in Lhasa, plateau region
[Objective] Exploring the clinical diagnosis and treatment status of epilepsy patients at the epilepsy specialty clinic in a single-center comprehensive hospital in the Lhasa area of the Tibetan Plateau. [Methods] Epilep...