Expert consensus on the clinical application of niacin skin flush detection in psychiatry-Expert consensus of CSNP psychiatric disorders research alliance (2024 edition)
Journal Title: Chinese Journal of Nervous and Mental Diseases - Year 2024, Vol 50, Issue 11
Abstract
Attenuated niacin skin response is a known biological endophenotype of psychotic disorders. By measuring the degree of erythema induced by niacin, about 30% of psychiatric disorders can be identified as having this characteristic, which may be related to the pathophysiological mechanisms of phospholipid-inflammatory imbalance. This detection provides new prevention and treatment strategies for clinicians. To further promote the clinical application and operational standards of this technique, the Chinese Society of Neuroscience & Psychiatry (CSNP) Psychotic Disorders Research Alliance discussed and formulated the “Expert Consensus on the Clinical Application of Niacin Skin Response Detection in Psychiatry”. This consensus delved into the physiological mechanisms of niacin skin reactions, their abnormal mechanisms associated with psychotic disorders, detection methods, defining criteria, evidence as biomarkers for psychotic disorders, auxiliary diagnostic value, and clinical intervention measures. Expert recommendations were formulated regarding the necessity of this detection, its scope of application, standardization of procedures, interpretation of results, targeted interventions, and its value in early screening and prevention.
Authors and Affiliations
Chinese Society of Neuroscience & Psychiatry (CSNP) Psychiatric Disorders Research Alliance.
Keywords
Related Articles
- EP ID EP759205
- DOI 10.3969/j.issn.1002-0152.2024.11.001
- Views 1
- Downloads 0
Optimizing multi-domain hematologic biomarkers and clinical features for the differential diagnosis of unipolar depression and bipolar depression
[Objective] This study aims to build a differential diagnosis model for unipolar and bipolar depression based on clinical features and blood indicators. [Methods] According to inclusion and exclusion criteria, participan...
Clinical study about ictal facial dystonia of medial temporal lobe epilepsy
[Objective] To study the clinical and electrophysiological characteristics about ictal facial dystonia of medial temporal lobe epilepsy. [Method] Data was collected from patients with mesial temporal lobe epilepsy origin...
Research progress on the application of light therapy in patients with bipolar depression
Existing antidepressant treatments are generally suboptimal for patients with bipolar disorder (BD). Several studies have explored the efficacy of light therapy (LT) in patients with bipolar depression, along with invest...
Progress of long chain non-coding RNAs in the inflammatory response to cerebral ischemia-reperfusion injury
Inflammatory response is one of the key mechanisms of cerebral ischemia/reperfusion injury (CIRI), which seriously affects the prognosis of patients. In recent years, it has been found that long non-coding RNA (LncRNA) i...
A case of spinocerebellar ataxia type 8 presenting with multiple system atrophy cerebral type
We report a case of spinocerebellar ataxia type 8 (SCA8) presenting with multisystem atrophic phenotype. The patient was a 57-year-old male with a 4-year course of illness with dizziness and ataxia as the first symptoms,...