Exploring the Potential of Lotus Leaf and Its Bioactive Compounds for Anti-obesity Interventions
Journal Title: Journal of Experimental and Clinical Application of Chinese Medicine - Year 2024, Vol 5, Issue 1
Abstract
The complex syndrome of obesity is a complex syndrome associated with various metabolic disorders, poses significant threats to human health. Many weight loss medications have the potential to rapidly treat obesity, however their toxicity and adverse effects may compromise patients' physiological and psychological well-being. In China, the concept of drug and food homology has been utilized for thousands of years, with lotus leaves serving as a representative example. The lotus leaves have been traditionally used for heat-clearing and lipid-lowering purposes, as well as for cooling the blood and promoting hemostasis, since ancient times. This review represents the first attempt to qualitatively investigate the anti-obesity properties of lotus leaves by integrating gene-disease association databases and drug-target databases for analysis. Additionally, it summarizes the identified monomers in lotus leaves that have been reported to possess functions associated with anti-obesity. The aim of this study is to provide a comprehensive review of the research progress on anti-obesity drugs derived from lotus leaves, and to facilitate further research and development in the field of anti-obesity medication targeting adiposity.
Authors and Affiliations
Lei Chen, Xinyi Zhang, Wei Zhang, Yuwei Liu
Keywords
Related Articles
- EP ID EP746602
- DOI https://doi.org/10.62767/jecacm501.2109
- Views 30
- Downloads 0
Exploring the Mechanism of Astragalus membranaceus in the Treatment of Post-Infectious Irritable Bowel Syndrome Based on Random Walk with Restart Algorithm and Experimental Validation
Background: This study aims to screen target genes with high relevance by running the random walk with restart (RWR) algorithm on the target background network, and to explore the mechanism of Astragalus membranaceus (AM...
Effect of Jinhuahecha—A Fermented Green Tea on DSS-Induced Ulcerative Colitis in Mice and Its Preliminary Pharmacological Mechanism
Background: Ulcerative colitis (UC) is an inflammatory bowel disease. Jinhuahecha (JHHC)-a fermented green tea is obtained by micro-fermentation of Anji white tea (AJWT) inoculated with high-purity "E. cristatum". Purpos...
Akabane Test—Its Capabilities and Real Application in Traditional and Modern Medicine
Background: Currently, for high-quality monitoring of the body, it is necessary to have many different devices with you and transmit their data to the doctor. It's expensive, complicated and ineffective. To solve this pr...
Dynamic Changes of Phytohormone Concentrations during Prunella vulgaris L. Development and Impact of Rosmarinic Acid Accumulation through Exogenous ABA Application
Background: Plant hormones not only participate in regulating the growth and development process of plants, but also play an important regulatory role in the synthesis of secondary metabolites. Prunella vulgaris L. (P. v...
Andrographolide: A Review on Experimental Clinical Trials and Applications
Throughout human history, plants have been used for medicinal purposes. Plants can synthesise a vast range of chemical compounds that possess biological activities and can be employed as medicines. Andrographis paniculat...