EXPLORING THE PROETECTIVE ROLE OF WATER EXTRACT OF SPIRULINA PLATENSIS ON GEMCITABINE-INDUCED LIPID PEROXIDATIONUSING COMMON LABORATORY MARKERS
Journal Title: Journal of Pharmaceutical and Scientific Innovation - Year 2018, Vol 7, Issue 3
Abstract
The present study was designed with an aim to explore the protective role of water extract of Spirulina platensison gemcitabine-induced lipid peroxidation. The work was carried out in vitroand goat liver was used as model lipid source. Two common laboratory markers such asmalondialdehyde and reduced glutathione were used for the model. The results showed thatgemcitabine has the ability to induce lipid peroxidation to a significant extent and it was also found that water extract of the Spirulina platensis has the ability to suppress the gemcitabine-induced toxicity.
Authors and Affiliations
Sarbani Dey Ray
Keywords
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- EP ID EP631008
- DOI 10.7897/2277-4572.07383
- Views 42
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