Expression of heat shock protein 90, 70, 60 and 25 in the placenta of Plasmodium berghei infected BALB/c mice
Journal Title: Asian Pacific Journal of Tropical Disease - Year 2014, Vol 4, Issue 0
Abstract
Objective: To assess the role of heat shock proteins (hsps) in the placental pathology of Plasmodium berghei infected mice. Methods: Female BALB/c mice were infected with Plasmodium berghei infected RBC intraperitoneally on 10th gestational day. The expression of hsps in the placenta were monitored by reverse transcriptase real time PCR. Results: There was increased expression of hsps 90, 70, 60 and 25 genes on day 2, 4 and 6 post infection in the infected placenta. However, the expression of hsps 70, 60 and 25 genes decreased with the progression of malaria infection. Conclusions: Decreased expression of hsps 70, 60 and 25 genes in the malaria infected placenta might be one of the many other factors responsible for apoptosis in the placenta and may be responsible for associated altered placental pathology and fetal abnormalities.
Pharmacognostic and clinical aspects of Cydonia oblonga: A review
Cydonia oblonga Miller (C. oblonga) is considered as an important medicinal plant throughout the world. It is native to Mediterranean region and Central Asia having a long term history of medicinal and ethnobotanical use...
Prevalence of severe chloroquine resistance associates the point mutation in pfcrt and pfmdrI gene in eastern India
Objective: To evaluate the molecular mechanism of chloroquine resistant Plasmodium falciparum malaria in West Bengal, eastern part, India. Methods: Parasitic bloods were collected from patients in Kolkata and Purulia, in...
Evaluation of CA-125 and other biochemical parameters in premenopausal and postmenopausal women with ovarian cancer: a hospital based study from Western Nepal
Objective: To assess the status of carbohydrate antigen 125 (CA-125) and other biochemical parameters in premenopausal and postmenopausal ovarian cancer patients. Methods: Total 64 cases, out of which 43 premenopausal an...
Evaluating correlation between serum liver enzymes and toxocariasis: a case control study
Objective: To evaluate the prevalence of toxocariasis in individuals with the normal and abnormal level of liver enzymes. Methods: In this case-control study, the serum samples were collected in the individuals referred...
Ribosomal DNA as molecular markers and their applications in the identification of fish parasites (Platyhelminthes: Monogenea) from India
The development of molecular techniques for taxonomic analysis of monogenean parasites has led to a great increase for proper identification and factualness. These molecular techniques, in particular the use of molecular...